Literature DB >> 24201059

Treatment considerations for early glottic carcinoma: lessons learned and a primer for the general otolaryngologist.

Nausheen Jamal1, Elazar Sofer, Dinesh K Chhetri.   

Abstract

In this commentary, we review our experience with early glottic carcinomas in an attempt to identify points to consider when developing a treatment protocol and technical considerations in oncologic resection to maintain laryngeal function. We highlight several consistent themes: (1) difficult exposure is not always a contraindication to endoscopic resection; (2) depth of invasion may be apparent only intraoperatively; (3) radiation therapy should be offered for deeply invasive cancers requiring extensive cordectomy or for patients who cannot afford lengthy vocal downtime; however, (4) radiation therapy leads to acute dysphagia and collateral damage to the contralateral vocal fold that is avoided with surgery; (5) good voice can be obtained after healing if resection is limited to intramuscular cordectomy; (6) the key to optimal vocal results is adequate glottal closure; and (7) second look operations are occasionally necessary, and therefore preoperative counseling should include this possibility. Since both surgery and radiation therapy achieve excellent oncologic control, a patient-centered approach is preferred in management.

Entities:  

Keywords:  endoscopic laryngectomy; glottic cancer; laryngeal dysplasia; radiation therapy; swallowing outcomes; voice outcomes

Mesh:

Year:  2013        PMID: 24201059     DOI: 10.1177/0194599813512101

Source DB:  PubMed          Journal:  Otolaryngol Head Neck Surg        ISSN: 0194-5998            Impact factor:   3.497


  3 in total

1.  When is surgical therapy for head and neck malignant epithelial tumors not indicated?

Authors:  Carlos Suárez; Robert P Takes; Carl E Silver; Juan P Rodrigo; Primož Strojan; Julia A Woolgar; Missak Haigentz; H Hakan Coskun; Remco de Bree; Randall P Owen; Mohamed N Elsheikh; Ashok R Shaha; Alessandra Rinaldo; Alfio Ferlito
Journal:  Eur Arch Otorhinolaryngol       Date:  2014-02-04       Impact factor: 2.503

2.  Efficacy of laser surgery versus radiotherapy for treatment of glottic carcinoma: a systematic review and meta-analysis.

Authors:  Yongxia Ding; Binquan Wang
Journal:  Lasers Med Sci       Date:  2018-12-06       Impact factor: 3.161

3.  Adverse histopathological findings in glottic cancer with anterior commissure involvement.

Authors:  Małgorzata Leszczyńska; Maciej Tokarski; Donata Jarmołowska-Jurczyszyn; Paweł Kosikowski; Witold Szyfter; Małgorzata Wierzbicka
Journal:  Eur Arch Otorhinolaryngol       Date:  2015-03-21       Impact factor: 2.503

  3 in total

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