Literature DB >> 24199557

[Studies on evaluation of sustained release tablets of extracts of Ginkgo biloba releasing rate in vitro by pharmacological indicatrix].

Pei-Pei Du1, Bo-Chen Zhao, Wen-Ping Wang, Jing An, Qiong Wang, Na Liu, Qing Wu, Wei Xiao.   

Abstract

Using sustained release tablets of Ginkgo bibolia extract as model drug,discuss technical feasibility of using biotic index to evaluate sustained release tablets. Chosing two pharmacological indicatrix: antioxidant ability and inhibition of platelet aggregation, to investigate the influence factors on experimental result, optimize the method and experiment condition, and set up pharmacological indicatrix evaluation method. Using those methods to determinate biological effects of dissolved liquid. Drawing release curves and biological effects curves, discussing their correlation. A good correlation was observed, illustrating that pharmacological indicatrix could evaluate sustained release tablets.

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Year:  2013        PMID: 24199557

Source DB:  PubMed          Journal:  Zhongguo Zhong Yao Za Zhi        ISSN: 1001-5302


  1 in total

1.  Simultaneous determination by UPLC-MS/MS of seven bioactive compounds in rat plasma after oral administration of Ginkgo biloba tablets: application to a pharmacokinetic study.

Authors:  Wen-ping Wang; Na Liu; Qian Kang; Pei-pei Du; Yi Lan; Bo-chen Zhao; Yan-yan Chen; Qing Zhang; Hui Li; Ye-wen Zhang; Qing Wu
Journal:  J Zhejiang Univ Sci B       Date:  2014-11       Impact factor: 3.066

  1 in total

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