| Literature DB >> 24198124 |
Kazumasa Zaima1, Daigo Wakana, Yosuke Demizu, Yukie Kumeta, Hiroyuki Kamakura, Takuro Maruyama, Masaaki Kurihara, Yukihiro Goda.
Abstract
A new amino acid-sesquiterpene adduct, isoheleproline (1), was isolated from the roots of Inula helenium (elecampane), together with four known sesquiterpene lactones (2-5). The planar configuration of 1 was elucidated on the basis of spectroscopic data analysis, and the relative configuration of 1 was determined by performing a detailed analysis of NOESY correlations and comparing its physicochemical data with the D- and L-proline adducts of 2 obtained by Michael addition. This is the first report of a new amino acid-sesquiterpene adduct from Inula plants.Entities:
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Year: 2013 PMID: 24198124 DOI: 10.1007/s11418-013-0806-8
Source DB: PubMed Journal: J Nat Med ISSN: 1340-3443 Impact factor: 2.343