Literature DB >> 24198124

Isoheleproline: a new amino acid-sesquiterpene adduct from Inula helenium.

Kazumasa Zaima1, Daigo Wakana, Yosuke Demizu, Yukie Kumeta, Hiroyuki Kamakura, Takuro Maruyama, Masaaki Kurihara, Yukihiro Goda.   

Abstract

A new amino acid-sesquiterpene adduct, isoheleproline (1), was isolated from the roots of Inula helenium (elecampane), together with four known sesquiterpene lactones (2-5). The planar configuration of 1 was elucidated on the basis of spectroscopic data analysis, and the relative configuration of 1 was determined by performing a detailed analysis of NOESY correlations and comparing its physicochemical data with the D- and L-proline adducts of 2 obtained by Michael addition. This is the first report of a new amino acid-sesquiterpene adduct from Inula plants.

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Year:  2013        PMID: 24198124     DOI: 10.1007/s11418-013-0806-8

Source DB:  PubMed          Journal:  J Nat Med        ISSN: 1340-3443            Impact factor:   2.343


  3 in total

1.  Sesquiterpenoids from Inula racemosa Hook. f. inhibit nitric oxide production.

Authors:  Shou-De Zhang; Jiang-Jiang Qin; Hui-Zi Jin; Yin-Hua Yin; Hong-Lin Li; Xian-Wen Yang; Xia Li; Lei Shan; Wei-Dong Zhang
Journal:  Planta Med       Date:  2011-10-14       Impact factor: 3.352

2.  Chemical analysis reveals the botanical origin of shatavari products and confirms the absence of alkaloid asparagamine A in Asparagus racemosus.

Authors:  Yukie Kumeta; Takuro Maruyama; Daigo Wakana; Hiroyuki Kamakura; Yukihiro Goda
Journal:  J Nat Med       Date:  2012-04-20       Impact factor: 2.343

3.  Saussureamines A, B, C, D, and E, new anti-ulcer principles from Chinese Saussureae Radix.

Authors:  M Yoshikawa; S Hatakeyama; Y Inoue; J Yamahara
Journal:  Chem Pharm Bull (Tokyo)       Date:  1993-01       Impact factor: 1.645

  3 in total
  3 in total

1.  From Monographs to Chromatograms: The Antimicrobial Potential of Inula helenium L. (Elecampane) Naturalised in Ireland.

Authors:  Ciara-Ruth Kenny; Anna Stojakowska; Ambrose Furey; Brigid Lucey
Journal:  Molecules       Date:  2022-02-18       Impact factor: 4.411

2.  Molecular Simulation Elaborating the Mechanism of 1β-Hydroxy Alantolactone Inhibiting Ubiquitin-Conjugating Enzyme UbcH5s.

Authors:  Youdong Xu; Xianli Meng
Journal:  Sci Rep       Date:  2020-01-10       Impact factor: 4.379

3.  Semisynthesis, an Anti-Inflammatory Effect of Derivatives of 1β-Hydroxy Alantolactone from Inula britannica.

Authors:  Lin Chen; Jian-Ping Zhang; Xin Liu; Jiang-Jiang Tang; Ping Xiang; Xing-Ming Ma
Journal:  Molecules       Date:  2017-10-27       Impact factor: 4.411

  3 in total

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