Literature DB >> 24197931

Vulnerable subjects? The case of nonhuman animals in experimentation.

Jane Johnson1.   

Abstract

The concept of vulnerability is deployed in bioethics to, amongst other things, identify and remedy harms to participants in research, yet although nonhuman animals in experimentation seem intuitively to be vulnerable, this concept and its attendant protections are rarely applied to research animals. I want to argue, however, that this concept is applicable to nonhuman animals and that a new taxonomy of vulnerability developed in the context of human bioethics can be applied to research animals. This taxonomy does useful explanatory work, helping to pinpoint the limitations of the 3Rs/welfare approach currently adopted in the context of animal experimentation. On this account, the 3Rs/welfare approach fails to deliver for nonhuman animals in experimentation because it effectively addresses only one element of their vulnerability (inherent) and paradoxically through the institution of Animal Ethics Committees intended to protect experimental animals in fact generates new vulnerabilities that exacerbate their already precarious situation.

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Year:  2013        PMID: 24197931     DOI: 10.1007/s11673-013-9473-4

Source DB:  PubMed          Journal:  J Bioeth Inq        ISSN: 1176-7529            Impact factor:   1.352


  5 in total

1.  Beyond "compliance": the role of institutional culture in promoting research integrity.

Authors:  Gail Geller; Alison Boyce; Daniel E Ford; Jeremy Sugarman
Journal:  Acad Med       Date:  2010-08       Impact factor: 6.893

2.  Vulnerability: what kind of principle is it?

Authors:  Michael H Kottow
Journal:  Med Health Care Philos       Date:  2004

3.  Factors influencing the effectiveness of research ethics committees.

Authors:  C A Schuppli; D Fraser
Journal:  J Med Ethics       Date:  2007-05       Impact factor: 2.903

4.  Where are we in the justification of research involving chimpanzees?

Authors:  Tom L Beauchamp; Hope R Ferdowsian; John P Gluck
Journal:  Kennedy Inst Ethics J       Date:  2012-09

5.  Challenges to the Development and Implementation of Public Policies to Achieve Animal Welfare Outcomes.

Authors:  Margaret Rose
Journal:  Animals (Basel)       Date:  2010-12-31       Impact factor: 2.752

  5 in total
  3 in total

1.  "As flies to wanton boys": dilemmas and dodging in the field of nonhuman animal ethics.

Authors:  Michael A Ashby; Leigh E Rich
Journal:  J Bioeth Inq       Date:  2013-12-10       Impact factor: 1.352

2.  Bioethics and nonhuman animals.

Authors:  Rob Irvine; Chris Degeling; Ian Kerridge
Journal:  J Bioeth Inq       Date:  2013-12       Impact factor: 1.352

3.  Chimpanzees as vulnerable subjects in research.

Authors:  Jane Johnson; Neal D Barnard
Journal:  Theor Med Bioeth       Date:  2014-04
  3 in total

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