| Literature DB >> 24197426 |
Abstract
Approximately 2% of the DNA of the mouse genome reassociates at infinitely low C 0 t values, 10(-7) to 10(-6) moles 1(-1) s. The melting profile of the reassociation product, which is resistant to nuclease S1 digestion, has been characterized by hydroxyapatite column chromatography. The properties of these nuclease resistant sequences suggest that they exist as 'DNA-hairpins' and that they originate from reverted base sequences within the genome.Entities:
Year: 1973 PMID: 24197426 DOI: 10.1007/BF00357401
Source DB: PubMed Journal: Mol Biol Rep ISSN: 0301-4851 Impact factor: 2.316