Literature DB >> 2419584

Antigenic binding sites of monoclonal antibodies specific for simian virus 40 large T antigen.

E G Gurney, S Tamowski, W Deppert.   

Abstract

We isolated 16 new monoclonal antibodies that recognize large T antigen of simian virus 40 and mapped the epitopes to three distinct regions of the large T antigen. Also, 3 of the 16 recognized the large T antigen of the human papovavirus BKV.

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Year:  1986        PMID: 2419584      PMCID: PMC252854     

Source DB:  PubMed          Journal:  J Virol        ISSN: 0022-538X            Impact factor:   5.103


  12 in total

1.  Rapid isolation of antigens from cells with a staphylococcal protein A-antibody adsorbent: parameters of the interaction of antibody-antigen complexes with protein A.

Authors:  S W Kessler
Journal:  J Immunol       Date:  1975-12       Impact factor: 5.422

2.  Continuous cultures of fused cells secreting antibody of predefined specificity.

Authors:  G Köhler; C Milstein
Journal:  Nature       Date:  1975-08-07       Impact factor: 49.962

3.  The genome of human papovavirus BKV.

Authors:  I Seif; G Khoury; R Dhar
Journal:  Cell       Date:  1979-12       Impact factor: 41.582

4.  Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

Authors:  H Towbin; T Staehelin; J Gordon
Journal:  Proc Natl Acad Sci U S A       Date:  1979-09       Impact factor: 11.205

5.  Precise determination of the entire antigenic structure of lysozyme: molecular features of protein antigenic structures and potential of "surface-simulation" synthesis--a powerful new concept for protein binding sites.

Authors:  M Z Atassi
Journal:  Immunochemistry       Date:  1978-12

6.  Analysis of the 84K, 55K, and 48K proteins immunoprecipitable by SV40 T antibody from SV40-infected and -transformed cells by tryptic peptide mapping on cation-exchange columns.

Authors:  D T Stitt; R B Carroll; J A Melero; W F Mangel
Journal:  Virology       Date:  1981-05       Impact factor: 3.616

7.  An immunochemical investigation of SV40 T antigens. 1. Production properties and specificity of rabbit antibody to purified simian virus 40 large-T antigen.

Authors:  D P Lane; A K Robbins
Journal:  Virology       Date:  1978-06-01       Impact factor: 3.616

8.  Evidence for simian virus 40 (SV40) coding of SV40 T-antigen and the SV40-specific proteins in HeLa cells infected with nondefective adenovirus type 2-SV40 hybrid viruses.

Authors:  K Mann; T Hunter; G Walter; H Linke
Journal:  J Virol       Date:  1977-10       Impact factor: 5.103

9.  SV40 large T shares an antigenic determinant with a cellular protein of molecular weight 68,000.

Authors:  D P Lane; W K Hoeffler
Journal:  Nature       Date:  1980-11-13       Impact factor: 49.962

10.  Monoclonal antibodies against simian virus 40 nuclear large T tumour antigen: epitope mapping, papova virus cross-reaction and cell surface staining.

Authors:  R K Ball; B Siegl; S Quellhorst; G Brandner; D G Braun
Journal:  EMBO J       Date:  1984-07       Impact factor: 11.598

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  58 in total

1.  Nonspecific DNA binding activity of simian virus 40 large T antigen: evidence for the cooperation of two regions for full activity.

Authors:  H J Lin; R H Upson; D T Simmons
Journal:  J Virol       Date:  1992-09       Impact factor: 5.103

2.  Structural basis for the interaction of a hexameric replicative helicase with the regulatory subunit of human DNA polymerase α-primase.

Authors:  Bo Zhou; Diana R Arnett; Xian Yu; Aaron Brewster; Gregory A Sowd; Charlies L Xie; Stefan Vila; Dahai Gai; Ellen Fanning; Xiaojiang S Chen
Journal:  J Biol Chem       Date:  2012-06-14       Impact factor: 5.157

3.  Large T-antigen double hexamers imaged at the simian virus 40 origin of replication.

Authors:  M Valle; C Gruss; L Halmer; J M Carazo; L E Donate
Journal:  Mol Cell Biol       Date:  2000-01       Impact factor: 4.272

4.  Specific interaction of simian virus 40 large T antigen with cellular chromatin and nuclear matrix during the course of infection.

Authors:  R Schirmbeck; W Deppert
Journal:  J Virol       Date:  1987-11       Impact factor: 5.103

5.  The N-terminal side of the origin-binding domain of simian virus 40 large T antigen is involved in A/T untwisting.

Authors:  L Chen; W S Joo; P A Bullock; D T Simmons
Journal:  J Virol       Date:  1997-11       Impact factor: 5.103

6.  Phenotype-specific phosphorylation of simian virus 40 tsA mutant large T antigens in tsA N-type and A-type transformants.

Authors:  U Knippschild; J Kiefer; T Patschinsky; W Deppert
Journal:  J Virol       Date:  1991-08       Impact factor: 5.103

7.  Large T-antigen mutants define multiple steps in the initiation of simian virus 40 DNA replication.

Authors:  I J Mohr; M P Fairman; B Stillman; Y Gluzman
Journal:  J Virol       Date:  1989-10       Impact factor: 5.103

8.  Comparison of the murine humoral immune response to recombinant simian virus 40 large tumor antigen: epitope specificity and idiotype expression.

Authors:  R K Bright; M H Shearer; R C Kennedy
Journal:  Cancer Immunol Immunother       Date:  1993-07       Impact factor: 6.968

9.  Simian virus 40 large-T-antigen-specific rejection of mKSA tumor cells in BALB/c mice is critically dependent on both strictly tumor-associated, tumor-specific CD8(+) cytotoxic T lymphocytes and CD4(+) T helper cells.

Authors:  O Utermöhlen; C Schulze-Garg; G Warnecke; R Gugel; J Löhler; W Deppert
Journal:  J Virol       Date:  2001-11       Impact factor: 5.103

10.  An N-terminal deletion mutant of simian virus 40 (SV40) large T antigen oligomerizes incorrectly on SV40 DNA but retains the ability to bind to DNA polymerase alpha and replicate SV40 DNA in vitro.

Authors:  K Weisshart; M K Bradley; B M Weiner; C Schneider; I Moarefi; E Fanning; A K Arthur
Journal:  J Virol       Date:  1996-06       Impact factor: 5.103

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