Literature DB >> 2419530

Expression of low molecular weight cytokeratin proteins in cervical neoplasia.

L G Bobrow, C A Makin, S Law, W F Bodmer.   

Abstract

CAM 5.2 is a monoclonal antibody which identifies lower molecular weight cytokeratin proteins (50, 43 and 38 kD). It is an antibody which works reliably on formalin-fixed, paraffin-embedded tissues. In this study, using CAM 5.2 in the indirect immunoperoxidase method we have examined ectocervical epithelium ranging from normal, through metaplasia and cervical intraepithelial neoplasia to invasive squamous carcinoma. CAM 5.2 is demonstrated to be a useful indicator of changes associated with malignant transformation in the ectocervix.

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Year:  1986        PMID： 2419530     DOI： 10.1002/path.1711480203

Source DB:  PubMed          Journal:  J Pathol        ISSN： 0022-3417            Impact factor:   7.996


  18 in total

Review 1.  Distribution of epithelial antigens in the human uterine cervix: a review.

Authors:  V Serra; A Ramirez; M C Marzo; F Valcuende; C Lara; A Castells; F Bonilla-Musoles
Journal:  Arch Gynecol Obstet       Date:  1989       Impact factor: 2.344

2.  Immunohistochemical study of possible changes in keratin expression during neoplastic transformation of the uterine mucosa.

Authors:  A Gernow; B Nielsen; B Hølund; P P Clausen
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1990

3.  Immunohistochemistry of cytokeratin proteins in squamous and transitional cell lesions of the urinary tract.

Authors:  M F Tungekar; K C Gatter; M S Al-Adnani
Journal:  J Clin Pathol       Date:  1988-12       Impact factor: 3.411

4.  Changing patterns of keratin expression during progression of cervical intraepithelial neoplasia.

Authors:  F Smedts; F Ramaekers; H Robben; M Pruszczynski; G van Muijen; B Lane; I Leigh; P Vooijs
Journal:  Am J Pathol       Date:  1990-03       Impact factor: 4.307

5.  Patterns of cytokeratin expression by neoplastic and non-neoplastic epithelium.

Authors:  G Mortimer; D N Jones; H Assaf; T al-Ahmadi
Journal:  Ir J Med Sci       Date:  1993-03       Impact factor: 1.568

6.  Identification of the MN antigen as a diagnostic biomarker of cervical intraepithelial squamous and glandular neoplasia and cervical carcinomas.

Authors:  S Y Liao; C Brewer; J Závada; J Pastorek; S Pastorekova; A Manetta; M L Berman; P J DiSaia; E J Stanbridge
Journal:  Am J Pathol       Date:  1994-09       Impact factor: 4.307

7.  Basal-cell keratins in cervical reserve cells and a comparison to their expression in cervical intraepithelial neoplasia.

Authors:  F Smedts; F Ramaekers; S Troyanovsky; M Pruszczynski; H Robben; B Lane; I Leigh; F Plantema; P Vooijs
Journal:  Am J Pathol       Date:  1992-03       Impact factor: 4.307

8.  Altered expression of proliferation and differentiation markers in human papillomavirus 16 and 18 immortalized epithelial cells grown in organotypic culture.

Authors:  D T Merrick; R A Blanton; A M Gown; J K McDougall
Journal:  Am J Pathol       Date:  1992-01       Impact factor: 4.307

9.  Detection of occult bone marrow micrometastases in patients with operable lung carcinoma.

Authors:  R J Cote; E J Beattie; B Chaiwun; S R Shi; J Harvey; S C Chen; A E Sherrod; S Groshen; C R Taylor
Journal:  Ann Surg       Date:  1995-10       Impact factor: 12.969

10.  Carcinomas of Bartholin's gland. Histogenesis and the etiological role of human papillomavirus.

Authors:  J C Felix; R J Cote; E E Kramer; P Saigo; G H Goldman
Journal:  Am J Pathol       Date:  1993-03       Impact factor: 4.307
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