| Literature DB >> 2419450 |
Abstract
A method is described for immunizing mice with a protein-cellulose complex obtained by covalent coupling of antigenic protein molecules to suspended cellulose particles. Primary immunization of the animals with the complex led to a pronounced immune response persisting for 20-30 days. Subsequent administration of the same antigen in a soluble form resulted in extremely active antibody formation equal to or better than that induced with Freund's complete adjuvant. In BALB/c mice the antibody response was about ten times greater than in the C57BL/6 strain.Entities:
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Year: 1986 PMID： 2419450 DOI： 10.1016/0022-1759(86)90526-0
Source DB: PubMed Journal: J Immunol Methods ISSN： 0022-1759 Impact factor: 2.303