Literature DB >> 24194051

Neuroblastoma cells as possible model in the study of glutamate receptors.

J B van der Valk1, H P Vijverberg.   

Abstract

The sensitivity of several cultured neuroblastoma cell lines toL-glutamate (Glu) and its analogues has been studied with the whole-cell patch clamp technique. Only in the neuroblastoma cell line N2A Glu induced a concentration dependent response consisting of an inward current. In addition, N2A cells responded to superfusion with kainate, quisqualate orN-methyl-D-aspartate, but to a lesser degree than to Glu. It is concluded that N2A cells could be useful as anin vitro model to study excitatory amino acid properties.

Entities:  

Year:  1991        PMID： 24194051     DOI： 10.1007/BF00808095

Source DB:  PubMed          Journal:  Amino Acids        ISSN： 0939-4451            Impact factor:   3.520


  6 in total

1.  Kinetics of the membrane current mediated by serotonin 5-HT3 receptors in cultured mouse neuroblastoma cells.

Authors:  H C Neijt; J J Plomp; H P Vijverberg
Journal:  J Physiol       Date:  1989-04       Impact factor: 5.182

2.  Properties of neuronal type acetylcholine receptors in voltage clamped mouse neuroblastoma cells.

Authors:  M Oortgiesen; H P Vijverberg
Journal:  Neuroscience       Date:  1989       Impact factor: 3.590

Review 3.  The physiology of excitatory amino acids in the vertebrate central nervous system.

Authors:  M L Mayer; G L Westbrook
Journal:  Prog Neurobiol       Date:  1987       Impact factor: 11.685

4.  Clonal cell lines from the rat central nervous system.

Authors:  D Schubert; S Heinemann; W Carlisle; H Tarikas; B Kimes; J Patrick; J H Steinbach; W Culp; B L Brandt
Journal:  Nature       Date:  1974-05-17       Impact factor: 49.962

5.  Characterization of a glutamic acid neurotransmitter binding site on neuroblastoma hybrid cells.

Authors:  A T Malouf; R L Schnaar; J T Coyle
Journal:  J Biol Chem       Date:  1984-10-25       Impact factor: 5.157

6.  Calcium-dependent glutamate cytotoxicity in a neuronal cell line.

Authors:  T H Murphy; A T Malouf; A Sastre; R L Schnaar; J T Coyle
Journal:  Brain Res       Date:  1988-03-22       Impact factor: 3.252
  6 in total
  3 in total

1.  Withanone, an Active Constituent from Withania somnifera, Affords Protection Against NMDA-Induced Excitotoxicity in Neuron-Like Cells.

Authors:  Nawab John Dar; Javeed Ahmad Bhat; Naresh Kumar Satti; Parduman Raj Sharma; Abid Hamid; Muzamil Ahmad
Journal:  Mol Neurobiol       Date:  2016-08-19       Impact factor: 5.590

2.  Beyond the heterodimer model for mineralocorticoid and glucocorticoid receptor interactions in nuclei and at DNA.

Authors:  John R Pooley; Caroline A Rivers; Michael T Kilcooley; Susana N Paul; Ayse Derya Cavga; Yvonne M Kershaw; Serena Muratcioglu; Attila Gursoy; Ozlem Keskin; Stafford L Lightman
Journal:  PLoS One       Date:  2020-01-10       Impact factor: 3.240

3.  Polymer microchamber arrays for geometry-controlled drug release: a functional study in human cells of neuronal phenotype.

Authors:  Olga Kopach; Kayiu Zheng; Olga A Sindeeva; Meiyu Gai; Gleb B Sukhorukov; Dmitri A Rusakov
Journal:  Biomater Sci       Date:  2019-05-28       Impact factor: 6.843
  3 in total

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