Marta Iglesias-Rey1, Manuel Barreiro-de Acosta, Francisco Caamaño-Isorna, Isabel V Rodríguez, Rocío Ferreiro, Björn Lindkvist, Aurelio L González, J E Dominguez-Munoz. 1. *Foundation for Research in Digestive Diseases (FIENAD); University Hospital of Santiago de Compostela, Santiago de Compostela, Spain; †Gastroenterology Clinic Hospital of Santiago de Compostela, Santiago de Compostela, Spain; ‡Department of Preventive Medicine and Public Health (CIBERESP), University of Santiago de Compostela, Santiago de Compostela, Spain; §Department of Clinical Psychology and Psychobiology, University of Santiago de Compostela, Santiago de Compostela, Spain; and ‖Department of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Abstract
BACKGROUND: The effect of different sociodemographic and clinical variables on the health-related quality of life (HRQOL) of patients with inflammatory bowel disease (IBD) is currently known, but the influence of psychological factors has not been sufficiently explored. The objective of this study was to identify psychological predictors of HRQOL in patients with IBD. METHODS: A cross-sectional prospective study was undertaken including 875 consecutive IBD patients. Independent variables were measured using a sociodemographic and clinical questionnaire, the Hospital Anxiety and Depression Scale (HADS) questionnaire, the Perceived Stress Scale (PSS) questionnaire, and the COPE questionnaire. Dependent variables were measured using the Short Form 36 Health Survey (SF-36) and the Inflammatory Bowel Disease Questionnaire (IBDQ-36). Logistic regression was performed to identify factors associated with HRQOL. RESULTS: The participation rate was 91.3%. Patients with IBD had a poorer HRQOL than the general population except on the Physical Function, Social Function, and Emotional Function Scale. Moreover, high levels of anxiety, depression, and stress were found to be associated with low levels in all quality of life measurements. No significant relationship was found between HRQOL and coping strategies. CONCLUSIONS: In patients with IBD, stress, anxiety and depression are important determinants of HRQOL and should therefore be considered in the management of this patient population.
BACKGROUND: The effect of different sociodemographic and clinical variables on the health-related quality of life (HRQOL) of patients with inflammatory bowel disease (IBD) is currently known, but the influence of psychological factors has not been sufficiently explored. The objective of this study was to identify psychological predictors of HRQOL in patients with IBD. METHODS: A cross-sectional prospective study was undertaken including 875 consecutive IBD patients. Independent variables were measured using a sociodemographic and clinical questionnaire, the Hospital Anxiety and Depression Scale (HADS) questionnaire, the Perceived Stress Scale (PSS) questionnaire, and the COPE questionnaire. Dependent variables were measured using the Short Form 36 Health Survey (SF-36) and the Inflammatory Bowel Disease Questionnaire (IBDQ-36). Logistic regression was performed to identify factors associated with HRQOL. RESULTS: The participation rate was 91.3%. Patients with IBD had a poorer HRQOL than the general population except on the Physical Function, Social Function, and Emotional Function Scale. Moreover, high levels of anxiety, depression, and stress were found to be associated with low levels in all quality of life measurements. No significant relationship was found between HRQOL and coping strategies. CONCLUSIONS: In patients with IBD, stress, anxiety and depression are important determinants of HRQOL and should therefore be considered in the management of this patient population.
Authors: Aoibhlinn O'Toole; Punyanganie S de Silva; Linda G Marc; Christine A Ulysse; Marcia A Testa; Amanda Ting; Alan Moss; Josh Korzenik; Sonia Friedman Journal: Inflamm Bowel Dis Date: 2018-01-18 Impact factor: 5.325
Authors: Edward L Barnes; Michael D Kappelman; Millie D Long; Donna M Evon; Christopher F Martin; Robert S Sandler Journal: Am J Gastroenterol Date: 2019-04 Impact factor: 10.864
Authors: Thiago H Freitas; Elias Andreoulakis; Gilberto S Alves; Hesley L L Miranda; Lúcia L B C Braga; Thomas Hyphantis; André F Carvalho Journal: World J Gastroenterol Date: 2015-06-07 Impact factor: 5.742
Authors: Alessandro Agostini; Marco Moretti; Carlo Calabrese; Fernando Rizzello; Paolo Gionchetti; Mauro Ercolani; Massimo Campieri Journal: Int J Colorectal Dis Date: 2014-07-19 Impact factor: 2.571
Authors: Divya Keerthy; Ada Youk; Arvind I Srinath; Nasuh Malas; Simona Bujoreanu; Athos Bousvaros; David Keljo; David R DeMaso; Eva M Szigethy Journal: J Pediatr Gastroenterol Nutr Date: 2016-12 Impact factor: 2.839
Authors: Gary R Lichtenstein; Edward V Loftus; Kim L Isaacs; Miguel D Regueiro; Lauren B Gerson; Bruce E Sands Journal: Am J Gastroenterol Date: 2018-03-27 Impact factor: 10.864
Authors: Lisa M Lix; Eric K H Chan; Richard Sawatzky; Tolulope T Sajobi; Juxin Liu; Wilma Hopman; Nancy Mayo Journal: Qual Life Res Date: 2015-11-20 Impact factor: 4.147
Authors: Cristina Calviño-Suárez; Rocío Ferreiro-Iglesias; Iria Bastón-Rey; Manuel Barreiro-de Acosta Journal: Int J Environ Res Public Health Date: 2021-07-04 Impact factor: 3.390