Literature DB >> 24192603

Gabapentinoid abuse in order to potentiate the effect of methadone: a survey among substance misusers.

Colin R W Baird1, Pauline Fox, Lesley A Colvin.   

Abstract

BACKGROUND/AIMS: There is emerging evidence of gabapentin and pregabalin (gabapentinoid) abuse, particularly in the substance misuse population, and some suggestion of gabapentinoids being abused alongside methadone.
METHODS: A questionnaire-based survey was carried out in six substance misuse clinics, looking for evidence of gabapentinoid abuse.
RESULTS: 22% (29/129) of respondents admitted to abusing gabapentinoids, and of these, 38% (11/29) abused gabapentinoids in order to potentiate the 'high' they obtained from methadone.
CONCLUSIONS: Gabapentinoid abuse along with methadone has not previously been described. These findings are of relevance to clinicians working within both substance misuse services and chronic pain services.
© 2013 S. Karger AG, Basel.

Entities:  

Mesh:

Substances:

Year:  2013        PMID: 24192603     DOI: 10.1159/000355268

Source DB:  PubMed          Journal:  Eur Addict Res        ISSN: 1022-6877            Impact factor:   3.015


  36 in total

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Journal:  CNS Drugs       Date:  2016-01       Impact factor: 5.749

2.  An Unusual Amnestic Syndrome Associated With Combined Fentanyl and Cocaine Use.

Authors:  Uzoma B Duru; Gauri Pawar; Jed A Barash; Liv E Miller; Indrani K Thiruselvam; Marc W Haut
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Review 3.  Abuse and Misuse of Pregabalin and Gabapentin.

Authors:  Kirk E Evoy; Megan D Morrison; Stephen R Saklad
Journal:  Drugs       Date:  2017-03       Impact factor: 9.546

4.  Abuse and diversion of gabapentin among nonmedical prescription opioid users in Appalachian Kentucky.

Authors:  Rachel V Smith; Michelle R Lofwall; Jennifer R Havens
Journal:  Am J Psychiatry       Date:  2015-05       Impact factor: 18.112

Review 5.  Misuse and abuse of pregabalin and gabapentin: cause for concern?

Authors:  Fabrizio Schifano
Journal:  CNS Drugs       Date:  2014-06       Impact factor: 5.749

6.  Abuse of combinations of gabapentin and quetiapine.

Authors:  Roy R Reeves; Randy S Burke
Journal:  Prim Care Companion CNS Disord       Date:  2014-09-11

7.  Patterns of gabapentin and pregabalin use and misuse: Results of a population-based cohort study in France.

Authors:  Damien Driot; Emilie Jouanjus; Stéphane Oustric; Julie Dupouy; Maryse Lapeyre-Mestre
Journal:  Br J Clin Pharmacol       Date:  2019-03-28       Impact factor: 4.335

Review 8.  Pharmacologic Treatment of Opioid Use Disorder: a Review of Pharmacotherapy, Adjuncts, and Toxicity.

Authors:  Michael S Toce; Peter R Chai; Michele M Burns; Edward W Boyer
Journal:  J Med Toxicol       Date:  2018-10-30

9.  Pregabalin Use Among Users of Illicit Drugs: A Cross-Sectional Survey in Southern Germany.

Authors:  Brendan J Snellgrove; Tilman Steinert; Susanne Jaeger
Journal:  CNS Drugs       Date:  2017-10       Impact factor: 5.749

10.  Factors Associated with Gabapentin Misuse among People Who Inject Drugs in Appalachian Kentucky.

Authors:  Mance E Buttram; Hilary L Surratt
Journal:  Subst Use Misuse       Date:  2020-09-11       Impact factor: 2.164

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