Literature DB >> 2419165

Primary structure of the alpha-subunit of bovine adenylate cyclase-inhibiting G-protein deduced from the cDNA sequence.

T Nukada, T Tanabe, H Takahashi, M Noda, K Haga, T Haga, A Ichiyama, K Kanagawa, M Hiranaga.   

Abstract

The primary structure of the alpha-subunit of the adenylate cyclase-inhibiting G-protein (Gi) has been deduced from the nucleotide sequence of cloned DNA complementary to the bovine cerebral mRNA encoding the polypeptide. A much higher degree of amino acid sequence homology is observed between the alpha-subunits of Gi and transducin (68%) than between those of Gi and the adenylate cyclase-stimulating G-protein (Gs) (43%) or between those of transducin and Gs (42%).

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Year:  1986        PMID： 2419165     DOI： 10.1016/0014-5793(86)80347-7

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  28 in total

1.  Expansion of signal transduction by G proteins. The second 15 years or so: from 3 to 16 alpha subunits plus betagamma dimers.

Authors:  Lutz Birnbaumer
Journal:  Biochim Biophys Acta       Date:  2006-12-15

2.  Deduced amino acid sequence of bovine retinal Go alpha: similarities to other guanine nucleotide-binding proteins.

Authors:  K P Van Meurs; C W Angus; S Lavu; H F Kung; S K Czarnecki; J Moss; M Vaughan
Journal:  Proc Natl Acad Sci U S A       Date:  1987-05       Impact factor: 11.205

3.  Molecular cloning and characterization of cDNA encoding the GTP-binding protein alpha i and identification of a related protein, alpha h.

Authors:  T Michel; J W Winslow; J A Smith; J G Seidman; E J Neer
Journal:  Proc Natl Acad Sci U S A       Date:  1986-10       Impact factor: 11.205

4.  A second form of the beta subunit of signal-transducing G proteins.

Authors:  B Gao; A G Gilman; J D Robishaw
Journal:  Proc Natl Acad Sci U S A       Date:  1987-09       Impact factor: 11.205

5.  Sequence analysis of cDNA and genomic DNA for a putative pertussis toxin-insensitive guanine nucleotide-binding regulatory protein alpha subunit.

Authors:  M Matsuoka; H Itoh; T Kozasa; Y Kaziro
Journal:  Proc Natl Acad Sci U S A       Date:  1988-08       Impact factor: 11.205

6.  Gi2 mediates alpha 2-adrenergic inhibition of adenylyl cyclase in platelet membranes: in situ identification with G alpha C-terminal antibodies.

Authors:  W F Simonds; P K Goldsmith; J Codina; C G Unson; A M Spiegel
Journal:  Proc Natl Acad Sci U S A       Date:  1989-10       Impact factor: 11.205

7.  Guanine nucleotides mediate stimulatory and inhibitory effects on cerebral-cortical membrane phospholipase C activity.

Authors:  I Litosch
Journal:  Biochem J       Date:  1989-07-01       Impact factor: 3.857

8.  Molecular cloning and characterization of GPA1, a G protein alpha subunit gene from Arabidopsis thaliana.

Authors:  H Ma; M F Yanofsky; E M Meyerowitz
Journal:  Proc Natl Acad Sci U S A       Date:  1990-05       Impact factor: 11.205

9.  The gene for the alpha i1 subunit of human guanine nucleotide binding protein maps near the cystic fibrosis locus.

Authors:  D B Bloch; K D Bloch; M Iannuzzi; F S Collins; E J Neer; J G Seidman; C C Morton
Journal:  Am J Hum Genet       Date:  1988-06       Impact factor: 11.025

10.  Antibody specific to the alpha subunit of the guanine nucleotide-binding regulatory protein Go: developmental appearance and immunocytochemical localization in brain.

Authors:  K J Chang; W Pugh; S G Blanchard; J McDermed; J P Tam
Journal:  Proc Natl Acad Sci U S A       Date:  1988-07       Impact factor: 11.205
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