| Literature DB >> 2419156 |
G R Taylor, G I Carter, T J Crow, J A Johnson, A F Fairbairn, E K Perry, R H Perry.
Abstract
The recovery of RNA from postmortem (PM) brain tissues was quantified by molecular hybridization. RNA degradation rates postmortem were faster in mice with herpes encephalitis than with uninfected mice, but clear ribosomal peaks could be seen up to 72 hr after death. In a comparison between frontal cortex samples from neurologically normal and Alzheimer's disease cases a reduction in ribosomal, poly A, preproenkephalin, and preprosomatostatin RNA levels was observed in the Alzheimer's disease group. This general reduction may be influenced by the cause of death as well as the pathology.Entities:
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Year: 1986 PMID： 2419156 DOI： 10.1016/0014-4800(86)90038-9
Source DB: PubMed Journal: Exp Mol Pathol ISSN： 0014-4800 Impact factor: 3.362