Literature DB >> 2419150

Calcium-dependent stimulation of acetylcholine release by substance P and vasoactive intestinal polypeptide.

W M Yau, J A Dorsett, M L Youther.   

Abstract

In the guinea-pig myenteric plexus-longitudinal muscle preparation from the small intestine, the release of acetylcholine evoked by substance P and vasoactive intestinal polypeptide was examined in vitro. Both neuropeptides stimulated efflux of [3H]acetylcholine from myenteric neurons in a calcium-dependent manner. This observation is consistent with the view that neurotransmitter release elicited by neuropeptides requires the presence of extracellular calcium ions.

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Year:  1986        PMID: 2419150     DOI: 10.1016/0014-2999(86)90547-9

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN: 0014-2999            Impact factor:   4.432


  5 in total

1.  Maturation of neuromodulatory effect of substance P in rabbit airways.

Authors:  D T Tanaka; M M Grunstein
Journal:  J Clin Invest       Date:  1990-02       Impact factor: 14.808

2.  The regulation of veratridine-stimulated electrogenic ion transport in mouse colon by neuropeptide Y (NPY), Y1 and Y2 receptors.

Authors:  Niall P Hyland; Helen M Cox
Journal:  Br J Pharmacol       Date:  2005-11       Impact factor: 8.739

3.  Alterations to enteric neural signaling underlie secretory abnormalities of the ileum in experimental colitis in the guinea pig.

Authors:  Ian M Hons; Joshua E Burda; John R Grider; Gary M Mawe; Keith A Sharkey
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2009-02-12       Impact factor: 4.052

4.  Airway brush cells generate cysteinyl leukotrienes through the ATP sensor P2Y2.

Authors:  Saltanat Ualiyeva; Nils Hallen; Yoshihide Kanaoka; Carola Ledderose; Ichiro Matsumoto; Wolfgang G Junger; Nora A Barrett; Lora G Bankova
Journal:  Sci Immunol       Date:  2020-01-17

5.  Interleukin-6 modulates colonic transepithelial ion transport in the stress-sensitive wistar kyoto rat.

Authors:  Dervla O'Malley; Timothy G Dinan; John F Cryan
Journal:  Front Pharmacol       Date:  2012-11-07       Impact factor: 5.810

  5 in total

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