Literature DB >> 24190678

Pediatric spinal epidural abscess: a 9-year institutional review and review of the literature.

Melody Hawkins1, Michael Bolton.   

Abstract

Spinal epidural abscess (SEA) is a rare condition that requires prompt diagnosis and initiation of treatment for optimal outcome. Treatment generally consists of surgical intervention and systemic antibiotics. We present 1 of the largest cohorts of nontuberculous pediatric SEA in the English literature, emphasizing the outcomes of conservative (ie, nonoperative) management. We retrospectively identified 9 pediatric patients (≤18 years of age) with SEAs at Our Lady of the Lake Children's Hospital from 2002 to 2011. Cases were reviewed for demographic, clinical, diagnostic, and treatment characteristics and outcomes. The diagnosis of SEA was made by MRI in all cases, and methicillin-resistant Staphylococcus aureus (MRSA) was the only identified pathogen, isolated via blood culture in 6 of 9 patients. Although every patient received systemic antibiotics, only 2 had neurosurgical intervention. Four of the 7 patients treated conservatively received computed tomography-guided needle drainage. All patients recovered without significant sequelae. SEA is a potentially fatal illness that necessitates a heightened clinical awareness for diagnosis and treatment. Although official recommendations regarding management in pediatrics are lacking, treatment has generally been surgical decompression and drainage in combination with antibiotics; recent reports have suggested that antibiotic therapy alone may be successful in select patient populations. Although the adult literature has suggested that such management can be trialed in specific situations, only a handful of cases in the pediatric literature have reported this nonoperative approach. We present one of the largest reviews in support of successfully treating SEA with nonsurgical therapy.

Entities:  

Keywords:  abscess; infection; pediatrics

Mesh:

Substances:

Year:  2013        PMID: 24190678     DOI: 10.1542/peds.2012-3805

Source DB:  PubMed          Journal:  Pediatrics        ISSN: 0031-4005            Impact factor:   7.124


  8 in total

Review 1.  Pediatric spinal infections-a review of non-tuberculous infections.

Authors:  Chandan B Mohanty; Graham Fieggen; Chandrashekhar E Deopujari
Journal:  Childs Nerv Syst       Date:  2018-07-03       Impact factor: 1.475

2.  Spinal epidural abscess.

Authors:  Prashanth Krishnamohan; Joseph R Berger
Journal:  Curr Infect Dis Rep       Date:  2014-11       Impact factor: 3.725

3.  Pediatric Holocord Epidural Abscess Treated with Apical Laminotomies with Catheter-directed Irrigation and Drainage.

Authors:  Elena Kurudza; James A Stadler
Journal:  Cureus       Date:  2019-09-23

4.  Successful Treatment of Pediatric Holo-Spinal Epidural Abscess With Percutaneous Drainage.

Authors:  Adam A Ammar; Mousa K Hamad; Malik S Obeidallah; Andrew J Kobets; Seon-Kyu Lee; Ira R Abbott
Journal:  Cureus       Date:  2022-05-04

Review 5.  Spinal epidural abscess from group A Streptococcus after varicella infection: a case report and review of the literature.

Authors:  G Cossu; M A Farhane; R T Daniel; M Messerer
Journal:  Childs Nerv Syst       Date:  2014-07-08       Impact factor: 1.475

6.  Pediatric Group A streptococcal spinal epidural abscess presenting with recurrent symptoms of viral illness: An operative case report.

Authors:  Khushdeep S Vig; Matthew Amarante; Ian Hutchinson; James Patrick Lawrence
Journal:  N Am Spine Soc J       Date:  2021-05-08

7.  Pediatric spinal epidural abscess in an immunocompetent host without risk factors: Case report and review of the literature.

Authors:  Alessandra Vergori; Alfonso Cerase; Lucia Migliorini; Maria Grazia Pluchino; Giuseppe Oliveri; Umberto Arrigucci; Andrea De Luca; Francesca Montagnani
Journal:  IDCases       Date:  2015-10-22

Review 8.  The Diagnosis and Management of Pediatric Spine Infections.

Authors:  Ehab S Saleh; Christopher C Vasileff; Abdullah M Omari; Jad G Khalil
Journal:  Cureus       Date:  2021-07-30
  8 in total

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