Literature DB >> 24189954

Physical map of the COB region in mitochondrial DNA of Saccharomyces cerevisiae.

G Grosch1, C Schmelzer, S Mathews.   

Abstract

A physical map of the COB region in mtDNA of yeast has been established. This region harbours a split gene coding for apocytochrome b. It includes restriction sites of seven endonucleases (EcoRI, HindII, HindIII, HaeIII, HpaII, AluI and BamHI). Various mtDNA sequences of this region, retained in a series of genetically characterized rho(-) clones have been allocated to this map. The combination of this physical map with a genetic map of the rho(-) clones revealed that 1) cob(-) mutational sites spread over 8,400 bp, 2) mutations in sequences coding for apocytochrome b map in five distinct segments which are separated by intervening sequences with minimum lengths from 350 to 1,900 bp.

Entities:  

Year:  1981        PMID： 24189954     DOI： 10.1007/BF00419582

Source DB:  PubMed          Journal:  Curr Genet        ISSN： 0172-8083            Impact factor:   3.886


  12 in total

1.  Regulatory interaction between mitochondrial genes. II. Detailed characterization of novel mutants mapping within one cluster in the cob2 region.

Authors:  D K Hanson; D H Miller; H R Mahler; N J Alexander; P S Perlman
Journal:  J Biol Chem       Date:  1979-04-10       Impact factor: 5.157

2.  Regulatory interactions between mitochondrial genes. I. Genetic and biochemical characterization of some mutant types affecting apocytochrome b and cytochrome oxidase.

Authors:  N J Alexander; R D Vincent; P S Perlman; D H Miller; D K Hanson; H R Mahler
Journal:  J Biol Chem       Date:  1979-04-10       Impact factor: 5.157

3.  A simple method for the large-scale preparation of mitochondria from microorganisms.

Authors:  B Lang; G Burger; I Doxiadis; D Y Thomas; W Bandlow; F Kaudewitz
Journal:  Anal Biochem       Date:  1977-01       Impact factor: 3.365

4.  Expression of the split gene COB in yeast mtDNA : Mutational arrest in the pathway of transcript splicing.

Authors:  A Haid; G Grosch; C Schmelzer; R J Schweyen; F Kaudewitz
Journal:  Curr Genet       Date:  1980-02       Impact factor: 3.886

5.  Mutations in putative intervening sequences of the mitochondrial cytochrome b gene of yeast produce abnormal cytochrome b polypeptides.

Authors:  M Solioz; G Schatz
Journal:  J Biol Chem       Date:  1979-10-10       Impact factor: 5.157

6.  [New mechanism for regulation of genetic expression].

Authors:  C Jacq; J Lazowska; P P Slonimski
Journal:  C R Seances Acad Sci D       Date:  1980-01-14

7.  A pathway of cytochrome b mRNA processing in yeast mitochondria: specific splicing steps and an intron-derived circular DNA.

Authors:  A Halbreich; P Pajot; M Foucher; C Grandchamp; P Slonimski
Journal:  Cell       Date:  1980-02       Impact factor: 41.582

8.  The mitochondrial COB region in yeast codes for apocytochrome b and is mosaic.

Authors:  A Haid; R J Schweyen; H Bechmann; F Kaudewitz; M Solioz; G Schatz
Journal:  Eur J Biochem       Date:  1979-03

9.  Physical mapping of genes on yeast mitochondrial DNA: localization of antibiotic resistance loci, and rRNA and tRNA genes.

Authors:  R Morimoto; S Merten; A Lewin; N C Martin; M Rabinowitz
Journal:  Mol Gen Genet       Date:  1978-07-25

10.  Mutations affecting RNA splicing and the interaction of gene expression of the yeast mitochondrial loci cob and oxi-3.

Authors:  G J Van Ommen; P H Boer; G S Groot; M De Haan; E Roosendaal; L A Grivell; A Haid; R J Schweyen
Journal:  Cell       Date:  1980-05       Impact factor: 41.582
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  1 in total

1.  Deletions in the cob gene of yeast mtDNA and their phenotypic effect.

Authors:  M Dobres; S Gerbl-Rieger; C Schmelzer; M W Mueller; R J Schweyen
Journal:  Curr Genet       Date:  1985       Impact factor: 3.886
  1 in total

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