Literature DB >> 24186317

Use of prothrombin complex concentrates for urgent reversal of dabigatran in the Emergency Department.

Manuel Quintana Díaz1, Alberto M Borobia, Ma Angelica Rivera Núñez, Ana Maria Martínez Virto, Sara Fabra, Marcelino Sánchez Casado, Jose A García-Erce, C Meyer Samama.   

Abstract

Entities:  

Keywords:  bleeding; dabigatran; prothrombin complex concentrate; reversal

Mesh:

Substances:

Year:  2013        PMID: 24186317      PMCID: PMC3815189          DOI: 10.3324/haematol.2013.092767

Source DB:  PubMed          Journal:  Haematologica        ISSN: 0390-6078            Impact factor:   9.941


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  11 in total

1.  Life-threatening bleeding in four patients with an unusual excessive response to dabigatran: implications for emergency surgery and resuscitation.

Authors:  Agnès Lillo-Le Louët; Martine Wolf; Lilia Soufir; Arnaud Galbois; Anne-Sylvie Dumenil; Georges Offenstadt; Meyer-Michel Samama
Journal:  Thromb Haemost       Date:  2012-07-10       Impact factor: 5.249

2.  Interpretation of point-of-care INR results in patients treated with dabigatran.

Authors:  Joanne van Ryn; Lawrence Baruch; Andreas Clemens
Journal:  Am J Med       Date:  2012-02-03       Impact factor: 4.965

3.  A novel user-friendly score (HAS-BLED) to assess 1-year risk of major bleeding in patients with atrial fibrillation: the Euro Heart Survey.

Authors:  Ron Pisters; Deirdre A Lane; Robby Nieuwlaat; Cees B de Vos; Harry J G M Crijns; Gregory Y H Lip
Journal:  Chest       Date:  2010-03-18       Impact factor: 9.410

4.  Prothrombin complex concentrates reduce blood loss in murine coagulopathy induced by warfarin, but not in that induced by dabigatran etexilate.

Authors:  M D Lambourne; L J Eltringham-Smith; S Gataiance; D M Arnold; M A Crowther; W P Sheffield
Journal:  J Thromb Haemost       Date:  2012-09       Impact factor: 5.824

5.  Reversal of dabigatran anticoagulation by prothrombin complex concentrate (Beriplex P/N) in a rabbit model.

Authors:  I Pragst; S H Zeitler; B Doerr; F J Kaspereit; E Herzog; G Dickneite; J van Ryn
Journal:  J Thromb Haemost       Date:  2012-09       Impact factor: 5.824

Review 6.  Dabigatran etexilate--a novel, reversible, oral direct thrombin inhibitor: interpretation of coagulation assays and reversal of anticoagulant activity.

Authors:  Joanne van Ryn; Joachim Stangier; Sebastian Haertter; Karl-Heinz Liesenfeld; Wolfgang Wienen; Martin Feuring; Andreas Clemens
Journal:  Thromb Haemost       Date:  2010-03-29       Impact factor: 5.249

7.  Rivaroxaban versus enoxaparin for thromboprophylaxis after total hip or knee arthroplasty: a meta-analysis of randomized controlled trials.

Authors:  Yong Bing Cao; Jun Dong Zhang; Hui Shen; Yuan Ying Jiang
Journal:  Eur J Clin Pharmacol       Date:  2010-09-02       Impact factor: 2.953

8.  Reversal of rivaroxaban and dabigatran by prothrombin complex concentrate: a randomized, placebo-controlled, crossover study in healthy subjects.

Authors:  Elise S Eerenberg; Pieter W Kamphuisen; Meertien K Sijpkens; Joost C Meijers; Harry R Buller; Marcel Levi
Journal:  Circulation       Date:  2011-09-06       Impact factor: 29.690

9.  Dabigatran versus warfarin in the treatment of acute venous thromboembolism.

Authors:  Sam Schulman; Clive Kearon; Ajay K Kakkar; Patrick Mismetti; Sebastian Schellong; Henry Eriksson; David Baanstra; Janet Schnee; Samuel Z Goldhaber
Journal:  N Engl J Med       Date:  2009-12-10       Impact factor: 91.245

10.  Switching from enoxaparin to dabigatran etexilate: pharmacokinetics, pharmacodynamics, and safety profile.

Authors:  Andreas Clemens; Joanne van Ryn; Regina Sennewald; Norio Yamamura; Joachim Stangier; Martin Feuring; Sebastian Härtter
Journal:  Eur J Clin Pharmacol       Date:  2012-01-18       Impact factor: 2.953

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  8 in total

Review 1.  The impact of prothrombin complex concentrates when treating DOAC-associated bleeding: a review.

Authors:  Maureane Hoffman; Joshua N Goldstein; Jerrold H Levy
Journal:  Int J Emerg Med       Date:  2018-12-03

Review 2.  Reversal of anticoagulant effects in patients with intracerebral hemorrhage.

Authors:  Sean Yates; Ravi Sarode
Journal:  Curr Neurol Neurosci Rep       Date:  2015-01       Impact factor: 5.081

3.  Management of new oral anticoagulants related life threatening or major bleedings in real life: a brief report.

Authors:  Luca Masotti; Gianni Lorenzini; Cristiana Seravalle; Grazia Panigada; Giancarlo Landini; Roberto Cappelli; Sam Schulman
Journal:  J Thromb Thrombolysis       Date:  2015-05       Impact factor: 2.300

Review 4.  Direct Oral Anticoagulants in Emergency Trauma Admissions.

Authors:  Marc Maegele; Oliver Grottke; Herbert Schöchl; Oliver A Sakowitz; Michael Spannagl; Jürgen Koscielny
Journal:  Dtsch Arztebl Int       Date:  2016-09-05       Impact factor: 5.594

Review 5.  New oral pharmacotherapeutic agents for venous thromboprophylaxis after total hip arthroplasty.

Authors:  Garrett B Aikens; Jacob R Osmundson; Michael P Rivey
Journal:  World J Orthop       Date:  2014-07-18

6.  Updates in the perioperative and emergency management of non-vitamin K antagonist oral anticoagulants.

Authors:  David Faraoni; Jerrold H Levy; Pierre Albaladejo; Charles-Marc Samama
Journal:  Crit Care       Date:  2015-04-29       Impact factor: 9.097

7.  Use of 4-factor prothrombin complex concentrate in the treatment of a gastrointestinal hemorrhage complicated by dabigatran.

Authors:  Terrance R McGovern; Justin J McNamee; Christopher Malabanan; Mohamed A Fouad; Nilesh Patel
Journal:  Int J Emerg Med       Date:  2015-04-15

Review 8.  Management of bleeding in patients treated with direct oral anticoagulants.

Authors:  Marcel Levi
Journal:  Crit Care       Date:  2016-08-20       Impact factor: 9.097

  8 in total

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