Mutant Gene snm2-1 (ts), conferring thermoconditional mutagen sensitivity in Saccharomyces cerevisiae, is allelic with RAD5.

Of two mutant genes (snm1-2 (ts) and snm2-1 (ts)) conferring thermoconditional mutagen sensitivity in Saccharomyces cerevisiae one (snm2-1 (ts)) is shown to be centromere-linked. At the restrictive temperature this allele reduces UV-induced back mutation frequency of the ochre allele hiss-2 but has no influence on forward mutation at the CAN1 locus. Complementation tests and recombination analysis revealed snm2 (ts) to be allelic with rad5 (rev2).