Literature DB >> 24185978

Effect of the phosphonic analogue of tyrosine on tyrosine iodination.

A Iron1, E Neuzil, A Cassaigne.   

Abstract

Depositing ofDL-1-amino-2-(p-hydroxyphenyl)-ethylphosphonic acid (Tyr-P) on the chicken embryo induced a dose dependent decrease of the iodine uptake by the embryonic thyroid. Tyr-P interfered on iodination of tyrosine when tested with hog thyroid peroxidase (TPO) and with bovine lactoperoxidase (LPO); the analogue was recognized by the two enzymes but its affinity for TPO and LPO was respectively 3 and 7 fold higher compared with that of the natural substrate, suggesting that Tyr-P may act as an iodine trap.

Entities:  

Year:  1994        PMID： 24185978     DOI： 10.1007/BF00808451

Source DB:  PubMed          Journal:  Amino Acids        ISSN： 0939-4451            Impact factor:   3.520


  10 in total

1.  Purification and iodinating activity of hog thyroid peroxidase.

Authors:  M L Coval; A Taurog
Journal:  J Biol Chem       Date:  1967-12-10       Impact factor: 5.157

2.  [Studies of the specificity of rat thyroid and hepatic iodotyrosine desiodase].

Authors:  R Michel; P Dumas; N Autissier
Journal:  C R Seances Soc Biol Fil       Date:  1969

3.  [Thyroid particulate peroxidase].

Authors:  J Pommier; S de Prailauné; J Nunez
Journal:  Biochimie       Date:  1972       Impact factor: 4.079

4.  The peroxidase-catalyzed oxidation of tyrosine.

Authors:  G S Bayse; A W Michaels; M Morrison
Journal:  Biochim Biophys Acta       Date:  1972-09-19

5.  [Synthesis and biological properties of the phosphonic analog of thyroxine].

Authors:  A M Lacoste; A Cassaigne; E Neuzil
Journal:  C R Acad Hebd Seances Acad Sci D       Date:  1968-11-25

6.  Catalysis of iodination by lactoperoxidase.

Authors:  M Morrison; G S Bayse
Journal:  Biochemistry       Date:  1970-07-21       Impact factor: 3.162

7.  Inhibition of iodotyrosine formation by analogs of tyrosine.

Authors:  L J Degroot; S Jaksina
Journal:  J Lab Clin Med       Date:  1969-08

8.  [Research on aminoalkylphosphonic acids. II. Iodine derivatives of the phosphonic analogue of tyrosine].

Authors:  A M Lacoste; A Cassaigne; E Neuzil
Journal:  Bull Soc Chim Biol (Paris)       Date:  1967

9.  Action of the phosphonic analogue of tyrosine and of other tyrosine derivatives on rat liver tyrosine aminotransferase.

Authors:  A Iron; E Neuzil; A Cassaigne
Journal:  Amino Acids       Date:  1993-02       Impact factor: 3.520

10.  Regulatory effects of iodide and thiocyanate on tyrosine oxidation catalyzed by thyroid peroxidase.

Authors:  J L Michot; J Osty; J Nunez
Journal:  Eur J Biochem       Date:  1980-06
  10 in total

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