Literature DB >> 2418592

The new biomedical technology.

C H Scoggin.   

Abstract

New methods for studying the genetic information of humans in health and disease are emerging from basic science laboratories. Because these approaches are yielding fundamental insights for diagnosing and treating disease, it is important that practitioners begin to understand these methods and how they are used. Methods for genetic analysis using recombinant DNA techniques consist of isolation, separation, propagation in microorganisms and molecular hybridization of DNA. The study of RNA allows determination of gene expression. These methods are being used to understand cancer, identify hereditary illness, produce pharmaceuticals and diagnose common clinical problems, such as infectious diseases.

Entities:  

Mesh:

Substances:

Year:  1985        PMID: 2418592      PMCID: PMC1306492     

Source DB:  PubMed          Journal:  West J Med        ISSN: 0093-0415


  34 in total

1.  Improved detection of the sickle mutation by DNA analysis: application to prenatal diagnosis.

Authors:  S H Orkin; P F Little; H H Kazazian; C D Boehm
Journal:  N Engl J Med       Date:  1982-07-01       Impact factor: 91.245

2.  A sensitive new prenatal test for sickle-cell anemia.

Authors:  J C Chang; Y W Kan
Journal:  N Engl J Med       Date:  1982-07-01       Impact factor: 91.245

3.  Human insulin from recombinant DNA technology.

Authors:  I S Johnson
Journal:  Science       Date:  1983-02-11       Impact factor: 47.728

4.  Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing.

Authors:  F Sanger; A R Coulson; B G Barrell; A J Smith; B A Roe
Journal:  J Mol Biol       Date:  1980-10-25       Impact factor: 5.469

5.  Construction and characterization of genomic libraries from specific human chromosomes.

Authors:  R Krumlauf; M Jeanpierre; B D Young
Journal:  Proc Natl Acad Sci U S A       Date:  1982-05       Impact factor: 11.205

6.  Identification of the constant chromosome regions involved in human hematologic malignant disease.

Authors:  J D Rowley
Journal:  Science       Date:  1982-05-14       Impact factor: 47.728

7.  The case of the misplaced gene.

Authors:  J L Marx
Journal:  Science       Date:  1982-12-03       Impact factor: 47.728

8.  Gene for hereditary retinoblastoma assigned to human chromosome 13 by linkage to esterase D.

Authors:  R S Sparkes; A L Murphree; R W Lingua; M C Sparkes; L L Field; S J Funderburk; W F Benedict
Journal:  Science       Date:  1983-02-25       Impact factor: 47.728

9.  Impact of genetic manipulation on society and medicine.

Authors:  A G Motulsky
Journal:  Science       Date:  1983-01-14       Impact factor: 47.728

10.  Selective growth in serum-free hormone-supplemented medium of tumor cells obtained by biopsy from patients with small cell carcinoma of the lung.

Authors:  D N Carney; P A Bunn; A F Gazdar; J A Pagan; J D Minna
Journal:  Proc Natl Acad Sci U S A       Date:  1981-05       Impact factor: 11.205

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.