Literature DB >> 24185429

Adherence and persistence associated with an appointment-based medication synchronization program.

David A Holdford, Timothy J Inocencio.   

Abstract

OBJECTIVE: To assess the impact of an appointment-based medication synchronization (ABMS) program on medication adherence and persistence with chronic medications. DESIGN Quasiexperimental study in which study patients were matched with control patients.
SETTING: Rural pharmacies in the Midwestern United States between June 30, 2011, and October 31, 2012. PATIENTS: Individuals receiving at least two refills for one of six categories of medications to treat chronic diseases (i.e., angiotensin-converting enzyme inhibitors or angiotensin receptor blockers, beta blockers, dihydropyridine calcium channel blockers, thiazide diuretics, metformin, statins). INTERVENTION: Patients in the ABMS program were compared with control patients receiving usual care. MAIN OUTCOME MEASURES: 1-year adherence rates using proportion of days covered (PDC) and 1-year nonpersistence rates.
RESULTS: Depending on the drug class, patients enrolled in the medication synchronization program (n = 47-81) had adherences rates of 66.1% to 75.5% during 1 year versus 37.0% to 40.8% among control patients. Program patients had 3.4 to 6.1 times greater odds of adherence compared with control patients. Control patients were 52% to 73% more likely to stop taking their chronic medications over 1 year.
CONCLUSION: An ABMS program in community pharmacies was associated with improved patient adherence and reduced likelihood of nonpersistence.

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Year:  2013        PMID: 24185429     DOI: 10.1331/JAPhA.2013.13082

Source DB:  PubMed          Journal:  J Am Pharm Assoc (2003)        ISSN: 1086-5802


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