Literature DB >> 24182650

[High flow, humidified-reheated oxygen therapy: a new oxygenation technique for adults].

J-P Frat1, V Goudet, C Girault.   

Abstract

Currently conventional oxygen therapy is the first choice symptomatic treatment in the management of acute respiratory failure (ARF). However, conventional oxygen therapy has important limitations which have lead to the development of heated and humidified high-flow nasal oxygen therapy (HFNO). HFNO is an innovative technique that can deliver, through special nasal cannulae, up to 100% of the inspired fraction (FiO2) with heated and humidified oxygen at a maximum flow of 70L/min. The characteristics of this technique (overcoming the patient's spontaneous inspiratory flow, heated humidification,) and its physiological effects (no dilution of FiO2, positive end-expiratory pressure, pharyngeal dead-space washout, decrease in airway resistance), allow efficient optimization of oxygenation with better tolerance for patients. Current data, mainly observational, show that HFNO could be used particularly for the management of hypoxemic ARF, notably in the more severe forms. Indications for using HFNO, alone or in association with noninvasive ventilation, are potentially very broad and may involve different types of ARF (post-operative, post-extubation, palliative care) and even the practice of invasive technical procedures (bronchial fibroscopy). However, though current studies are very encouraging and promise a clinical benefit on patient outcomes, randomized trials are still needed to demonstrate that HFNO avoids the need for endotracheal intubation in the management of ARF.
Copyright © 2013 SPLF. Published by Elsevier Masson SAS. All rights reserved.

Entities:  

Keywords:  Acute respiratory failure; Heated and humidified high-flow nasal oxygen therapy; Insuffisance respiratoire aiguë; Noninvasive ventilation; Oxygénothérapie à haut débit; Ventilation non invasive

Mesh:

Substances:

Year:  2013        PMID: 24182650     DOI: 10.1016/j.rmr.2013.04.016

Source DB:  PubMed          Journal:  Rev Mal Respir        ISSN: 0761-8425            Impact factor:   0.622


  3 in total

1.  Delaying intubation with high-flow nasal cannula therapy: a dilemma between the technique and clinical management!

Authors:  Christophe Girault; Gaëtan Béduneau; Emmanuel Besnier
Journal:  Intensive Care Med       Date:  2015-06-03       Impact factor: 17.440

Review 2.  High-flow nasal oxygen therapy and noninvasive ventilation in the management of acute hypoxemic respiratory failure.

Authors:  Jean-Pierre Frat; Rémi Coudroy; Nicolas Marjanovic; Arnaud W Thille
Journal:  Ann Transl Med       Date:  2017-07

Review 3.  Applications of Nasal High-Flow Oxygen Therapy in Critically ill Adult Patients.

Authors:  Jahan Porhomayon; Ali A El-Solh; Leili Pourafkari; Philippe Jaoude; Nader D Nader
Journal:  Lung       Date:  2016-05-03       Impact factor: 2.584

  3 in total

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