Gert L de Lange1, Janice R Overman2, Elisabet Farré-Guasch2, Clara M Korstjens2, Bastiaan Hartman2, Geerling E J Langenbach3, Marion A Van Duin2, Jenneke Klein-Nulend4. 1. Academic Center Oral Implantology Amstelveen, Amstelveen, The Netherlands. 2. Department of Oral Cell Biology, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam, and VU University Amsterdam, Amsterdam, The Netherlands; MOVE Research Institute Amsterdam, Amsterdam, The Netherlands. 3. Department of Functional Anatomy, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam, and VU University Amsterdam, Amsterdam, The Netherlands; MOVE Research Institute Amsterdam, Amsterdam, The Netherlands. 4. Department of Oral Cell Biology, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam, and VU University Amsterdam, Amsterdam, The Netherlands; MOVE Research Institute Amsterdam, Amsterdam, The Netherlands. Electronic address: j.kleinnulend@acta.nl.
Abstract
OBJECTIVE: The gain of mineralized bone was compared between deproteinized bovine bone allograft (DBA) and biphasic calcium phosphate (BCP) for dental implant placement. STUDY DESIGN: Five patients with atrophic maxillae underwent bilateral sinus elevation with DBA (Bio-Oss) and BCP (Straumann BoneCeramic). After 3 to 8 months, 32 Camlog implants were placed, and biopsies were retrieved. Bone and graft volume, degree of bone mineralization, and graft degradation gradient were determined using micro-computed tomography, and bone formation and resorption parameters were measured using histomorphometry. Implant functioning and peri-implant mucosa were evaluated up to 4 years. RESULTS: Patients were prosthetically successfully restored. All but one of the implants survived, and peri-implant mucosa showed healthy appearance and stability. Bone volume, graft volume, degree of bone mineralization, and osteoclast and osteocyte numbers were similar, but BCP-grafted biopsies had relatively more osteoid than DBA-grafted biopsies. CONCLUSIONS: The BCP and DBA materials showed similar osteoconductive patterns and mineralized bone, although signs of more active bone formation and remodeling were observed in BCP- than in DBA-grafted biopsies.
OBJECTIVE: The gain of mineralized bone was compared between deproteinized bovine bone allograft (DBA) and biphasic calcium phosphate (BCP) for dental implant placement. STUDY DESIGN: Five patients with atrophic maxillae underwent bilateral sinus elevation with DBA (Bio-Oss) and BCP (Straumann BoneCeramic). After 3 to 8 months, 32 Camlog implants were placed, and biopsies were retrieved. Bone and graft volume, degree of bone mineralization, and graft degradation gradient were determined using micro-computed tomography, and bone formation and resorption parameters were measured using histomorphometry. Implant functioning and peri-implant mucosa were evaluated up to 4 years. RESULTS:Patients were prosthetically successfully restored. All but one of the implants survived, and peri-implant mucosa showed healthy appearance and stability. Bone volume, graft volume, degree of bone mineralization, and osteoclast and osteocyte numbers were similar, but BCP-grafted biopsies had relatively more osteoid than DBA-grafted biopsies. CONCLUSIONS: The BCP and DBA materials showed similar osteoconductive patterns and mineralized bone, although signs of more active bone formation and remodeling were observed in BCP- than in DBA-grafted biopsies.
Authors: Justine Loin; Jean-Daniel Kün-Darbois; Bernard Guillaume; Smail Badja; Hélène Libouban; Daniel Chappard Journal: J Mater Sci Mater Med Date: 2019-08-22 Impact factor: 3.896
Authors: Johann Charwat-Pessler; Maurizio Musso; Alexander Petutschnigg; Karl Entacher; Bernhard Plank; Erik Wernersson; Stefan Tangl; Peter Schuller-Götzburg Journal: Materials (Basel) Date: 2015-06-25 Impact factor: 3.623
Authors: S A Alkaabi; D S Natsir Kalla; G A Alsabri; A Fauzi; A Tajrin; W E G Müller; H C Schröder; X G Wang; T Forouzanfar; M N Helder; M Ruslin Journal: Trials Date: 2021-06-14 Impact factor: 2.279
Authors: Daniele Bollati; Marco Morra; Clara Cassinelli; Saturnino Marco Lupi; Ruggero Rodriguez Y Baena Journal: Biomed Res Int Date: 2016-04-18 Impact factor: 3.411