Literature DB >> 241815

ORG 6001 (3alpha-amino-5alpha-androstan-2beta-ol-17-one hydrochloride), a steroidal anti-arrhythmic agent.

B B Vargaftig, M F Sugrue, W R Buckett, H van Riezen.   

Abstract

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Year:  1975        PMID： 241815     DOI： 10.1111/j.2042-7158.1975.tb09535.x

Source DB:  PubMed          Journal:  J Pharm Pharmacol        ISSN： 0022-3573            Impact factor:   3.765


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  8 in total

1.  Investigations to characterize a new anti-arrhythmic drug, ORG 6001 including a simple test for calcium antagonism.

Authors:  L A Salako; V Williams; J H Wittig
Journal:  Br J Pharmacol       Date:  1976-06       Impact factor: 8.739

2.  Coronary artery ligation in anaesthetized rats as a model for the assessment of antidysrhythmic activity; the effects of lignocaine, propranolol and ORG 6001 [proceedings].

Authors:  K Kane; F McDonald; J R Parratt
Journal:  Br J Pharmacol       Date:  1979-07       Impact factor: 8.739

3.  Proceedings of the British Pharmacological Society. 16--18th December, 1980.

Authors: 
Journal:  Br J Pharmacol       Date:  1981-05       Impact factor: 8.739

4.  Evaluation of antagonism of aconitine-induced dysrhythmias in mice as a method of detecting and assessing antidysrhythmic activity.

Authors:  E Winslow
Journal:  Br J Pharmacol       Date:  1980       Impact factor: 8.739

5.  Electrophysiological and other effects on rabbit hearts of CCI22277, a new steroidal antiarrhythmic drug.

Authors:  T J Campbell; E M Vaughan Williams
Journal:  Br J Pharmacol       Date:  1982-06       Impact factor: 8.739

6.  Comparative antidysrhythmic and haemodynamic effects of orally or intravenously administered mexiletine and ORG 6001 in the anaesthetized rat.

Authors:  R J Marshall; A W Muir; E Winslow
Journal:  Br J Pharmacol       Date:  1981-10       Impact factor: 8.739

7.  Antifibrillatory efficacy of encainide, loracainide and ORG 6001 compared with lignocaine in isolated hearts of rabbits and guinea-pigs.

Authors:  A A Almotrefi; J B Baker
Journal:  Br J Pharmacol       Date:  1981-06       Impact factor: 8.739

8.  The effect of aminosteroid, ORG 6001, on hypothermia induced ventricular fibrillation in the cat.

Authors:  K A Kane; F M McDonald; J R Parratt
Journal:  Br J Pharmacol       Date:  1979-08       Impact factor: 8.739
  8 in total

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