Literature DB >> 2418087

The haemostatic effects of hydroxyethyl starch (HES) used as a volume expander.

E Macintyre, I J Mackie, D Ho, J Tinker, C Bullen, S J Machin.   

Abstract

Hydroxyethyl starch (HES 450.000/0.7; Hespan 6.0 g/100 ml) was compared with standard crystalloid solutions in postoperative volume replacement in 20 patients undergoing routine orthopaedic surgery. The HES group showed no clinical evidence of haemorrhage and no laboratory evidence of significant haemostatic defects as assessed by standard coagulation tests, platelet aggregation and fibrinogen concentrations. There was a slight shortening in the thrombin time and a smaller increase in post-operative FVIII RAg and FVIII RCof levels in the HES group. HES is a safe and effective volume expander for postoperative use.

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Year:  1985        PMID： 2418087     DOI： 10.1007/bf00273540

Source DB:  PubMed          Journal:  Intensive Care Med        ISSN： 0342-4642            Impact factor:   17.440


  10 in total

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Journal:  Crit Care Med       Date:  1981-12       Impact factor: 7.598

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Journal:  Surgery       Date:  1967-10       Impact factor: 3.982

10.  Quantitative assay of a plasma factor deficient in von Willebrand's disease that is necessary for platelet aggregation. Relationship to factor VIII procoagulant activity and antigen content.

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  10 in total
  6 in total

Review 1.  Fluid replacement in hypovolaemia.

Authors:  E Macintyre; C Bullen; S J Machin
Journal:  Intensive Care Med       Date:  1985       Impact factor: 17.440

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Authors:  J Boldt; M Müller; M Heesen; O Heyn; G Hempelmann
Journal:  Intensive Care Med       Date:  1996-10       Impact factor: 17.440

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Authors:  Ornella Piazza; Giuliana Scarpati; Rosalba Tufano
Journal:  Int J Gen Med       Date:  2010-10-05

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Authors:  R E Collis; P W Collins; C N Gutteridge; A Kaul; A C Newland; D M Williams; A R Webb
Journal:  Intensive Care Med       Date:  1994       Impact factor: 17.440
  6 in total

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