BACKGROUND: Treatment for advanced laryngeal cancer includes surgery, and/or chemoradiotherapy or radiotherapy. Each of these treatments results in major changes to the swallowing mechanism. Dysphagia is strongly correlated with poorer quality of life. A good understanding of outcomes is needed for well-informed treatment decisions. METHOD: This study reports on patients' swallowing outcomes following surgical and non-surgical treatments based on the results of three different swallowing tests. A total of 123 data sets were collected in out-patient clinics across two hospitals in North East England. RESULTS: There were no significant differences between treatment groups for patient-reported swallowing outcomes or swallowing performance. However, patients who had undergone chemoradiotherapy or radiotherapy (with or without laryngectomy) had significantly more diet restrictions than other groups. CONCLUSION: Long-term dysphagia is a common outcome of treatment for advanced laryngeal cancer. Patients treated with chemoradiotherapy and laryngectomy reported the worst overall outcomes. More longitudinal prospective research with large treatment groups is needed to investigate swallowing outcomes following different treatment methods.
BACKGROUND: Treatment for advanced laryngeal cancer includes surgery, and/or chemoradiotherapy or radiotherapy. Each of these treatments results in major changes to the swallowing mechanism. Dysphagia is strongly correlated with poorer quality of life. A good understanding of outcomes is needed for well-informed treatment decisions. METHOD: This study reports on patients' swallowing outcomes following surgical and non-surgical treatments based on the results of three different swallowing tests. A total of 123 data sets were collected in out-patient clinics across two hospitals in North East England. RESULTS: There were no significant differences between treatment groups for patient-reported swallowing outcomes or swallowing performance. However, patients who had undergone chemoradiotherapy or radiotherapy (with or without laryngectomy) had significantly more diet restrictions than other groups. CONCLUSION: Long-term dysphagia is a common outcome of treatment for advanced laryngeal cancer. Patients treated with chemoradiotherapy and laryngectomy reported the worst overall outcomes. More longitudinal prospective research with large treatment groups is needed to investigate swallowing outcomes following different treatment methods.
Authors: Alana Aylward; Sarah Abdelaziz; Jason P Hunt; Luke O Buchmann; Richard B Cannon; Shane Lloyd; Ying Hitchcock; Mia Hashibe; Marcus M Monroe Journal: Otolaryngol Head Neck Surg Date: 2019-06-11 Impact factor: 3.497
Authors: Laura W J Baijens; Margaret Walshe; Leena-Maija Aaltonen; Christoph Arens; Reinie Cordier; Patrick Cras; Lise Crevier-Buchman; Chris Curtis; Wojciech Golusinski; Roganie Govender; Jesper Grau Eriksen; Kevin Hansen; Kate Heathcote; Markus M Hess; Sefik Hosal; Jens Peter Klussmann; C René Leemans; Denise MacCarthy; Beatrice Manduchi; Jean-Paul Marie; Reza Nouraei; Claire Parkes; Christina Pflug; Walmari Pilz; Julie Regan; Nathalie Rommel; Antonio Schindler; Annemie M W J Schols; Renee Speyer; Giovanni Succo; Irene Wessel; Anna C H Willemsen; Taner Yilmaz; Pere Clavé Journal: Eur Arch Otorhinolaryngol Date: 2020-12-19 Impact factor: 2.503
Authors: Maha Al-Gilani; S Andrew Skillington; Dorina Kallogjeri; Bruce Haughey; Jay F Piccirillo Journal: JAMA Otolaryngol Head Neck Surg Date: 2016-10-01 Impact factor: 6.223
Authors: Femke Jansen; Ingrid C Cnossen; Simone E J Eerenstein; Veerle M H Coupé; Birgit I Witte; Cornelia F van Uden-Kraan; Patricia Doornaert; Weibel W Braunius; Remco De Bree; José A U Hardillo; Jimmie Honings; György B Halmos; C René Leemans; Irma M Verdonck-de Leeuw Journal: BMC Cancer Date: 2016-08-02 Impact factor: 4.430
Authors: Femke Jansen; Veerle M H Coupé; Simone E J Eerenstein; C René Leemans; Irma M Verdonck-de Leeuw Journal: Support Care Cancer Date: 2017-11-03 Impact factor: 3.603