OBJECTIVES: The objective of the current review was to use published data to assess the role of [18F] fluorodeoxyglucose-positron emission tomography (FDG-PET) as a complementary modality to computed-tomography (CT) in radiotherapy target volume delineation for head and neck cancer (HNC). METHODS: Studies were identified by searching PubMed electronic databases. Both prospective and retrospective studies were included. Information regarding the role of FDG-PET for radiotherapy target volume delineation for HNC was analyzed. RESULTS: FDG-PET is a promising tool for improving radiotherapy target volume delineation by defining a metabolically active biological target volume (BTV). The use of novel PET tracers representing properties such as hypoxia, protein synthesis and proliferation remain to be better characterized. CONCLUSIONS: The role of FDG-PET for radiotherapy target volume delineation for patients with HNC is expanding and should be further evaluated in clinical trials.
OBJECTIVES: The objective of the current review was to use published data to assess the role of [18F] fluorodeoxyglucose-positron emission tomography (FDG-PET) as a complementary modality to computed-tomography (CT) in radiotherapy target volume delineation for head and neck cancer (HNC). METHODS: Studies were identified by searching PubMed electronic databases. Both prospective and retrospective studies were included. Information regarding the role of FDG-PET for radiotherapy target volume delineation for HNC was analyzed. RESULTS:FDG-PET is a promising tool for improving radiotherapy target volume delineation by defining a metabolically active biological target volume (BTV). The use of novel PET tracers representing properties such as hypoxia, protein synthesis and proliferation remain to be better characterized. CONCLUSIONS: The role of FDG-PET for radiotherapy target volume delineation for patients with HNC is expanding and should be further evaluated in clinical trials.
Entities:
Keywords:
FDG-PET; Head and neck cancer; Radiotherapy target volumes
Authors: Stephen L Breen; Julia Publicover; Shiroma De Silva; Greg Pond; Kristy Brock; Brian O'Sullivan; Bernard Cummings; Laura Dawson; Anne Keller; John Kim; Jolie Ringash; Eugene Yu; Aaron Hendler; John Waldron Journal: Int J Radiat Oncol Biol Phys Date: 2007-03-26 Impact factor: 7.038
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