Literature DB >> 241787

Effects of a human plasma fraction on the release of chemotactic factors and anaphylatoxin from complement.

J R Walker, J K Badcock, A W Ford-Hutchinson, M J Smith, F J Billimoria.   

Abstract

A fraction prepared from normal human plasma inhibits the release of chemotactic factors and anaphylatoxin when complement is activated by the alternate but not by the classical pathway. The fraction gave no interference with the actions of the released substances on either leucocytes or guinea-pig isolated ileum. The possible relation of this effect to the mechanism of the anti-inflammatory actions of the plasma fraction is discussed.

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Year:  1975        PMID: 241787     DOI: 10.1111/j.2042-7158.1975.tb09394.x

Source DB:  PubMed          Journal:  J Pharm Pharmacol        ISSN: 0022-3573            Impact factor:   3.765


  2 in total

1.  An anti-inflammatory substance in normal human plasma.

Authors:  M J Smith; A W Ford-Hutchinson
Journal:  Agents Actions       Date:  1975-10

2.  Directed migration of circulating polymorphonuclear leucocytes in patients with rheumatoid arthritis: a defect in the plasma.

Authors:  J R Walker; D W James; M J Smith
Journal:  Ann Rheum Dis       Date:  1979-06       Impact factor: 19.103

  2 in total

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