Photophysical properties ofβ-homo-tyrosine derivatives.

The observed monoexponential fluorescence decay of N-acetyl-β-homo-tyrosine methylamide (Ac-βHty-NHMe) (I) and N-acetyl-(O-methyl)-β-homo-tyrosine methylamide (Ac-βHty(OMe)-NHMe) (II) is supporting the rotamer population theory, according to which rotamers are responsible for heterogeneity of the fluorescence decay of N-acetyl-tyrosine amide or tyrosine incorporated within a peptide chain, in general.