Literature DB >> 24177910

ALG/alg: a single gene controlling the utilization of lactate in the presence of antimycin in the yeast Saccharomyces cerevisiae.

I Ferrero1, R Rambaldelli, A M Genga, C Donnini, P P Puglisi.   

Abstract

A strain dependent growth on lactate in the presence of antimycin A (AA) has been observed - the strain D261 can grow on lactate and AA, whereas in the strain K8/6C antimycin A prevents the utilization of lactate and the induction of LDH.Genetic analysis demonstrates that growth on lactate in the presence of AA segregates from D261 as a single nuclear factor which we indicate by ALG1 and alg1 in its dominant and recessive states. alg1 complements the gene(s) which give(s) rise to the same phenotype in K8/6C.The analysis of the regulation by lactate of LDH in the absence and presence of AA and in rho (-) cells shows that growth on lactate and antimycin A is not corretated with the induction by lactate of LDH.

Entities:  

Year:  1984        PMID： 24177910     DOI： 10.1007/BF00433906

Source DB:  PubMed          Journal:  Curr Genet        ISSN： 0172-8083            Impact factor:   3.886


  8 in total

1.  [INDUCTION OF LACTATE-CYTOCHROME C REDUCTASES (D- AND L-) OF AEROBIC YEAST BY LACTATES (D- AND L-)].

Authors:  M SOMLO
Journal:  Biochim Biophys Acta       Date:  1965-02-15

2.  Lactic dehydrogenase of yeast. III. A comparative study of the kinetic properties and the stability of two isolated forms of the enzyme.

Authors:  A P NYGAARD
Journal:  Biochim Biophys Acta       Date:  1960-05-06

3.  [The difference in stereospecificity between the lactic dehydrogenase extracted from anaerobic yeast and that extracted from aerobic yeast].

Authors:  F LABEYRIE; P P SLONIMSKI; L NASLIN
Journal:  Biochim Biophys Acta       Date:  1959-07

4.  Utilization by yeast of D-lactate and L-lactate as sources of energy in the presence of antimycin A.

Authors:  P Pajot; M L Claisse
Journal:  Eur J Biochem       Date:  1974-11-01

5.  Ethidium bromide induced mutation of yeast mitochondria: complete transformation of cells into respiratory deficient non-chromosomal "petites".

Authors:  P P Slonimski; G Perrodin; J H Croft
Journal:  Biochem Biophys Res Commun       Date:  1968-02-15       Impact factor: 3.575

6.  [Presence and regulation of the synthesis of D-LDH in aerobic yeast].

Authors:  M Somlo
Journal:  Bull Soc Chim Biol (Paris)       Date:  1966

7.  Mitochondrial NAD, L-lactate dehydrogenase and NAD, D-lactate dehydrogenase in the yeast Saccharomyces cerevisiae.

Authors:  A M Genga; F Tassi; T Lodi; I Ferrero
Journal:  Microbiologica       Date:  1983-01

8.  The biogenesis of mitochondria in Saccharomyces cerevisiae. A comparison between cytoplasmic respiratory-deficient mutant yeast and chlormaphenicol-inhibited wild type cells.

Authors:  G D Clark-Walker; A W Linnane
Journal:  J Cell Biol       Date:  1967-07       Impact factor: 10.539
  8 in total

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