Literature DB >> 24177519

Inhibitors of the dicarboxylate and tricarboxylate transporting systems of rat liver mitochondria.

B H Robinson1, G R Williams, M L Halperin, C C Leznoff.   

Abstract

A large number of compounds were tested for their effectiveness as inhibitors of the tricarboxylate and dicarboxylate transporting systems of rat liver mitochondria as monitored by citrate/[(14)C] citrate exchange and phosphate/[(14)C]L-malate exchange, respectively. The influence of inhibitor structure on inhibitory potency is discussed for each transporting system and deductions made concerning the nature of the binding sites of these carrier systems.

Entities:  

Year:  1972        PMID： 24177519     DOI： 10.1007/BF01867928

Source DB:  PubMed          Journal:  J Membr Biol        ISSN： 0022-2631            Impact factor:   1.843


  10 in total

1.  The effect of mitochondrial oxidations of inhibitors of the dicarboxylate anion transporting system.

Authors:  B H. Robinson; G R. Williams
Journal:  FEBS Lett       Date:  1969-11-29       Impact factor: 4.124

2.  Kinetics of succinate uptake by rat-liver mitochondria.

Authors:  E Quagliariello; F Palmieri; G Prezioso; M Klingenberg
Journal:  FEBS Lett       Date:  1969-08       Impact factor: 4.124

3.  Penetration of the mitochondrial membrane by tricarboxylic acid anions.

Authors:  J B Chappell; B H Robinson
Journal:  Biochem Soc Symp       Date:  1968

4.  The effects of 2-ethylcitrate and tricarballylate on citrate transport in rat liver mitochondria and fatty acid synthesis in rat white adipose tissue.

Authors:  B H Robinson; G R Williams; M L Halperin; C C Leznoff
Journal:  Eur J Biochem       Date:  1970-08

5.  The inhibition of malate, tricarboxylate and oxoglutarate entry into mitochondria by 2-n-butylmalonate.

Authors:  B H Robinson; J B Chappell
Journal:  Biochem Biophys Res Commun       Date:  1967-07-21       Impact factor: 3.575

6.  Factors affecting the kinetics and equilibrium of exchange reactions of the citrate-transporting system of rat liver mitochondria.

Authors:  B H Robinson; G R Williams; M L Halperin; C C Leznoff
Journal:  J Biol Chem       Date:  1971-09-10       Impact factor: 5.157

7.  The sensitivity of dicarboxylate anion exchange reactions o transport inhibitors in rat-liver mitochondria.

Authors:  B H Robinson; G R Williams
Journal:  Biochim Biophys Acta       Date:  1970-08-04

8.  The effect of malate and other dicarboxylic acids on mitochondrial isocitrate metabolism.

Authors:  S M Ferguson; G R Williams
Journal:  J Biol Chem       Date:  1966-08-25       Impact factor: 5.157

9.  The kinetics of tricarboxylate anion oxidation by rat liver mitochondria in relation to the availability of L-malate.

Authors:  B H Robinson; J B Chappell
Journal:  Biochim Biophys Acta       Date:  1970

10.  The sensitivity of the exchange reactions of tricarboxylate, 2-oxoglutarate and dicarboxylate transporting systems of rat liver mitochondria to inhibition by 2-pentylmalonate, p-iodobenzylmalonate, and benzene 1,2,3-tricarboxylate.

Authors:  B H Robinson; G R Williams; M L Halperin; C C Leznoff
Journal:  Eur J Biochem       Date:  1971-05-11
  10 in total
  3 in total

1.  Phosphate transport in rat liver mitochondria. Kinetics, inhibitor sensitivity, energy requirements, and labeled components.

Authors:  W A Coty; P L Pedersen
Journal:  Mol Cell Biochem       Date:  1975-11-14       Impact factor: 3.396

Review 2.  The mitochondrial tricarboxylate carrier.

Authors:  A Azzi; M Glerum; R Koller; W Mertens; S Spycher
Journal:  J Bioenerg Biomembr       Date:  1993-10       Impact factor: 2.945

3.  The hypolipidemic activity of benzenetricarboxylic acids in rodents.

Authors:  I H Hall; J M Chapman; C Gilbert
Journal:  Pharm Res       Date:  1984-03       Impact factor: 4.200
  3 in total

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