| Literature DB >> 24176637 |
Josep Rizo1, Junjie Xu2.
Abstract
Diverse roles in membrane fusion have been proposed for the transmembrane regions (TMRs) of SNARE proteins, including formation of channel-like transmembrane pores. Reporting in Neuron, Zhou et al. (2013) show that lipid-anchored SNAREs lacking TMRs can support neurotransmitter release, suggesting that SNAREs function primarily as power engines that force membranes together.Entities:
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Year: 2013 PMID： 24176637 DOI： 10.1016/j.devcel.2013.10.010
Source DB: PubMed Journal: Dev Cell ISSN： 1534-5807 Impact factor: 12.270