Melek Kezban Gürbüz1, Mustafa Açikalin2, Soner Tasar3, Hamdi Cakli4, Göknur Yorulmaz5, Metin Erdinç6, Erkan Özüdoğru4, Cem Keçik4, Ertuğrul Colak7, Suzan Saylisoy8. 1. Eskisehir Osmangazi University, Faculty of Medicine, Department of Otorhinolaryngology, Turkey. Electronic address: mkezban@yahoo.com.tr. 2. Eskisehir Osmangazi University, Faculty of Medicine, Department of Pathology, Turkey. 3. Eskisehir Government Hospital, Turkey. 4. Eskisehir Osmangazi University, Faculty of Medicine, Department of Otorhinolaryngology, Turkey. 5. Batman Regional Hospital, Turkey. 6. Medical Park Hospital, Uşak, Turkey. 7. Eskisehir Osmangazi University, Faculty of Medicine, Department of Biostatistics, Turkey. 8. Eskisehir Osmangazi University, Faculty of Medicine, Department of Radiology, Turkey.
Abstract
OBJECTIVE: The incidence of thyroid gland invasion in patients with advanced laryngeal cancer was reported to be 0-50%. However there is a controversy in necessity and extent of routine thyroidectomy in these patients due to the difficulty in diagnosis of tumor invasion to thyroid gland and the risk of possible postoperative hypothyroidism and hypocalcemia. METHODS: The medical files of 47 patients who underwent thyroidectomy as part of surgical treatment for advanced laryngeal cancer were reviewed. RESULTS: Fourty-four (93.6%) patients underwent hemithyroidectomy, 3 (6.3%) patients underwent total thyroidectomy. Thyroid gland invasion was found in 2 (4.2%) patients. Hypothyroidism occurred in 15 (31.9%) patients, and their hormone levels were regulated with medical treatment during follow-up. Hypocalcemia was not found in any patients. CONCLUSION: We recommend that at least a hemithyroidectomy should be performed in patients with advanced laryngeal cancer, if they have any predictive factor (subglottic extension more than 1cm, invasion of paraglottic space, thyroid cartilage, cricoid cartilage and prelaryngeal tissue detected by radiological examination) for thyroid gland invasion.
OBJECTIVE: The incidence of thyroid gland invasion in patients with advanced laryngeal cancer was reported to be 0-50%. However there is a controversy in necessity and extent of routine thyroidectomy in these patients due to the difficulty in diagnosis of tumor invasion to thyroid gland and the risk of possible postoperative hypothyroidism and hypocalcemia. METHODS: The medical files of 47 patients who underwent thyroidectomy as part of surgical treatment for advanced laryngeal cancer were reviewed. RESULTS: Fourty-four (93.6%) patients underwent hemithyroidectomy, 3 (6.3%) patients underwent total thyroidectomy. Thyroid gland invasion was found in 2 (4.2%) patients. Hypothyroidism occurred in 15 (31.9%) patients, and their hormone levels were regulated with medical treatment during follow-up. Hypocalcemia was not found in any patients. CONCLUSION: We recommend that at least a hemithyroidectomy should be performed in patients with advanced laryngeal cancer, if they have any predictive factor (subglottic extension more than 1cm, invasion of paraglottic space, thyroid cartilage, cricoid cartilage and prelaryngeal tissue detected by radiological examination) for thyroid gland invasion.
Authors: May El-Sebai Ali; Hisham Atef Ebada; Mahmoud Abd El-Shaheed; Ahmed Musaad AbdElFattah; El Sharawy Kamal Journal: Ann Med Surg (Lond) Date: 2022-01-31