Literature DB >> 24175943

Meta-analysis shows limited evidence for using Lactobacillus acidophilus LB to treat acute gastroenteritis in children.

Hania Szajewska1, Marek Ruszczyński, Sanja Kolaček.   

Abstract

UNLABELLED: A meta-analysis of four randomised controlled trials of varying methodological quality, involving 304 children aged 1-48 months, showed that Lactobacillus acidophilus LB (LB) reduced the duration of diarrhoea in hospitalised, but not outpatient, children compared with a placebo. The chance of a cure on day three was similar in both groups, but LB increased the chance of cure on day four.
CONCLUSION: There is limited evidence to recommend LB for treating paediatric diarrhoea. ©2013 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

Entities:  

Keywords:  Diarrhoea; Microbiota; Probiotics; RCT; Systematic review

Mesh：

Year:  2013        PMID： 24175943     DOI： 10.1111/apa.12487

Source DB:  PubMed          Journal:  Acta Paediatr        ISSN： 0803-5253            Impact factor:   2.299


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