Literature DB >> 24175339

Palladium-catalyzed carbonylative synthesis of quinazolinones from 2-aminobenzamide and aryl bromides.

Xiao-Feng Wu, Lin He, Helfried Neumann, Matthias Beller.   

Abstract

C from CO! A straightforward procedure for the carbonylative synthesis of quinazolinones from readily available 2-aminobenzamide and aryl bromides has been developed. In the presence of a palladium catalyst, various quinazolinones were produced in moderate to excellent yields. Remarkably, no chromatography was needed for purification (see scheme).

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Year:  2013        PMID: 24175339     DOI: 10.1002/chem.201302182

Source DB:  PubMed          Journal:  Chemistry        ISSN: 0947-6539            Impact factor:   5.236


  4 in total

Review 1.  A decennary update on applications of metal nanoparticles (MNPs) in the synthesis of nitrogen- and oxygen-containing heterocyclic scaffolds.

Authors:  Tejas M Dhameliya; Hiren A Donga; Punit V Vaghela; Bhoomi G Panchal; Dipen K Sureja; Kunjan B Bodiwala; Mahesh T Chhabria
Journal:  RSC Adv       Date:  2020-09-03       Impact factor: 4.036

2.  "On-Water" Synthesis of Quinazolinones and Dihydroquinazolinones Starting from o-Bromobenzonitrile.

Authors:  Zibin Liu; Li-Yan Zeng; Chao Li; Fubiao Yang; Fensheng Qiu; Shuwen Liu; Baomin Xi
Journal:  Molecules       Date:  2018-09-12       Impact factor: 4.411

3.  Metal-free synthesis of 1,4-benzodiazepines and quinazolinones from hexafluoroisopropyl 2-aminobenzoates at room temperature.

Authors:  Jiewen Chen; En Liang; Jie Shi; Yinrong Wu; Kangmei Wen; Xingang Yao; Xiaodong Tang
Journal:  RSC Adv       Date:  2021-01-28       Impact factor: 3.361

4.  Synthesis, antitumor activity, 3D-QSAR and molecular docking studies of new iodinated 4-(3H)-quinazolinones 3N-substituted.

Authors:  Marcia Pérez-Fehrmann; Víctor Kesternich; Arturo Puelles; Víctor Quezada; Fernanda Salazar; Philippe Christen; Jonathan Castillo; Juan Guillermo Cárcamo; Alejandro Castro-Alvarez; Ronald Nelson
Journal:  RSC Adv       Date:  2022-08-02       Impact factor: 4.036

  4 in total

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