| Literature DB >> 24174038 |
Akira Yanagisawa1, Takuya Sugita, Kazuhiro Yoshida.
Abstract
Go catalytic! A catalytic enantioselective protonation of alkenyl trifluoroacetates was achieved by using an in situ generated chiral tin bromide methoxide as the chiral catalyst in the presence of methanol. Optically active ketones containing a tertiary stereogenic center at the α-position were obtained with enantioselectivities of up to 94 % ee.Entities:
Keywords: alkenyl esters; asymmetric catalysis; ketones; protonation; tin
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Year: 2013 PMID： 24174038 DOI： 10.1002/chem.201302975
Source DB: PubMed Journal: Chemistry ISSN： 0947-6539 Impact factor: 5.236