Literature DB >> 24173303

A quantitative evaluation of the relative efficiency of gelatine and albumin in preventing insulin adsorption to glass.

P H Sönksen1, J P Ellis, C Lowy, A Rutherford, J D Nabarro.   

Abstract

Albumin has been found to be more effective than gelatine in preventing insulin loss from insulin containing solutions. It is probable that this has led to falsely elevated levels of insulin-like activity (ILA) reported with bio-assays. Preparations of crystalline human albumin have been found to be free from ILA and from insulin measured by the radio-immuno-assay. Other human albumin prepared by acid-ethanol extraction (that has been shown previously to contain insulin antagonistic properties on the isolated rat hemidiaphragm) has contained significant ILA on the isolated rat fat pad and also contained insulin demonstrable by radio-immuno-assay.

Entities:  

Year:  1966        PMID： 24173303     DOI： 10.1007/BF01257913

Source DB:  PubMed          Journal:  Diabetologia        ISSN： 0012-186X            Impact factor:   10.122


  8 in total

1.  EFFECT OF THE INSULIN-INHIBITORY ALBUMIN FRACTION FROM NORMAL AND DIABETIC SUBJECTS ON ADIPOSE TISSUE.

Authors:  H ALP; L RECANT
Journal:  Metabolism       Date:  1964-07       Impact factor: 8.694

2.  PROPERTIES OF HUMAN "ALBUMIN". A METABOLIC STUDY OF ALBUMIN EXTRACTS FROM NORMAL AND DIABETIC PLASMA.

Authors:  H KEEN
Journal:  Diabetes       Date:  1963 Sep-Oct       Impact factor: 9.461

3.  Immunoassay of insulin with insulin-antibody precipitate.

Authors:  C N HALES; P J RANDLE
Journal:  Biochem J       Date:  1963-07       Impact factor: 3.857

4.  The adsorption of I131-insulin to glass.

Authors:  J B HILL
Journal:  Endocrinology       Date:  1959-09       Impact factor: 4.736

5.  Antagonism of insulin by albumin.

Authors:  C LOWY; G BLANSHARD; D PHEAR
Journal:  Lancet       Date:  1961-04-15       Impact factor: 79.321

6.  Lack of specificity of insulin-I 131-binding by isolated rat diaphragm.

Authors:  K NEWERLY; S A BERSON
Journal:  Proc Soc Exp Biol Med       Date:  1957-04

7.  The separation of protein fractions from human plasma with ether.

Authors:  R A KEKWICK; M E MACKAY
Journal:  Spec Rep Ser Med Res Counc (G B)       Date:  1954

8.  Insulin and adrenocorticotropin labelled with radio-iodine.

Authors:  J W FERREBEE; B B JOHNSON; J C MITHOEFER; J W GARDELLA
Journal:  Endocrinology       Date:  1951-03       Impact factor: 4.736
  8 in total
  5 in total

1.  Sensitization of adipose tissue to insulin by rat serum.

Authors:  R Guidoux; G Möhren; G Peters
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1974       Impact factor: 3.000

2.  Synalbumin, its isolation and conservation.

Authors:  D McMaster; J Vallance-Owen
Journal:  Acta Diabetol Lat       Date:  1974 Nov-Dec

3.  Serum insulin in acromegaly. Comparative investigations by a radio-immunological method and the biological methods using adipose and muscle tissue.

Authors:  H Liebermeister; H G Solbach; W H Schilling; R Rüenauver; H Meissner; D Grüneklee; L Herberg; H Daweke
Journal:  Diabetologia       Date:  1968-08       Impact factor: 10.122

4.  Advantage in management of diabetic coma by intensive care.

Authors:  P Singer; A Rahn; V Schliack
Journal:  Acta Diabetol Lat       Date:  1977 May-Aug

5.  Course and prognosis of 86 episodes of diabetic coma. A five year experience with a uniform schedule of treatment.

Authors:  U Keller; W Berger; R Ritz; P Truog
Journal:  Diabetologia       Date:  1975-04       Impact factor: 10.122
  5 in total

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