Literature DB >> 24170031

MicroRNA associated with dyslipidemia and coronary disease in humans.

Elena Flowers1, Bradley E Aouizerat.   

Abstract

MicroRNAs are structural components of an epigenetic mechanism of posttranscriptional regulation of messenger RNA translation. Recently, there has been significant interest in the application of microRNA as a blood-based biomarker of underlying physiological conditions. Dyslipidemia is a complex, heterogeneous condition conferring substantially increased risk for cardiovascular disease. The purpose of this review is to describe the current body of knowledge on the role of microRNA regulation of lipoprotein metabolism in humans and to discuss relevant methodological and study design considerations. We highlight the potential roles for microRNA in gene-environment interactions.

Entities:  

Keywords:  lipids; microRNA

Mesh：

Substances：

Year:  2013        PMID： 24170031      PMCID： PMC3882685          DOI： 10.1152/physiolgenomics.00106.2013

Source DB:  PubMed          Journal:  Physiol Genomics        ISSN： 1094-8341            Impact factor:   3.107


  60 in total

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Journal:  Nature       Date:  2011-10-19       Impact factor: 49.962
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