AIMS: Left atrial (LA) size has been related to the success of radiofrequency catheter ablation (RFCA) for atrial fibrillation (AF). However, potential predictors after a repeated procedure are unknown. We evaluate predictive factors related to successful AF ablation after a first and a repeated RFCA. METHODS AND RESULTS: A total of 154 patients with AF were treated with RFCA. LA size and function were assessed with three-dimensional echocardiography (3D Echo) before RFCA. The effectiveness of RFCA was evaluated after 6 months. Recurrence of the arrhythmia was defined as any documented (clinically or by 24-h Holter recording) atrial tachyarrhythmia lasting >30 s after 12 weeks following RFCA. Of 154 patients, 103 (67%) underwent a first ablation (Group 1) and 51 (33%) a repeated RFCA (Group 2). At follow-up, arrhythmias were eliminated in 56 of 103 (54%) patients after a first RFCA and in 20 of 51 (40%) after a repeated ablation. In Group I, hypertension and LA expansion index derived from 3D Echo were independent predictors of arrhythmia elimination. In Group 2, only age predicted persistence of sinus rhythm; and only in younger patients (≤54 year old), though 3D LA maximal volumes were significantly smaller in those without when compared with those with AF recurrences. CONCLUSION: A combination of the analysis of LA function with 3D Echo and clinical data predicts elimination of AF after a first ablation procedure for AF, beyond LA size. Among patients undergoing a repeated procedure, age and 3D echocardiographic LA maximum volume in younger patients predict the success of RFCA.
AIMS: Left atrial (LA) size has been related to the success of radiofrequency catheter ablation (RFCA) for atrial fibrillation (AF). However, potential predictors after a repeated procedure are unknown. We evaluate predictive factors related to successful AF ablation after a first and a repeated RFCA. METHODS AND RESULTS: A total of 154 patients with AF were treated with RFCA. LA size and function were assessed with three-dimensional echocardiography (3D Echo) before RFCA. The effectiveness of RFCA was evaluated after 6 months. Recurrence of the arrhythmia was defined as any documented (clinically or by 24-h Holter recording) atrial tachyarrhythmia lasting >30 s after 12 weeks following RFCA. Of 154 patients, 103 (67%) underwent a first ablation (Group 1) and 51 (33%) a repeated RFCA (Group 2). At follow-up, arrhythmias were eliminated in 56 of 103 (54%) patients after a first RFCA and in 20 of 51 (40%) after a repeated ablation. In Group I, hypertension and LA expansion index derived from 3D Echo were independent predictors of arrhythmia elimination. In Group 2, only age predicted persistence of sinus rhythm; and only in younger patients (≤54 year old), though 3D LA maximal volumes were significantly smaller in those without when compared with those with AF recurrences. CONCLUSION: A combination of the analysis of LA function with 3D Echo and clinical data predicts elimination of AF after a first ablation procedure for AF, beyond LA size. Among patients undergoing a repeated procedure, age and 3D echocardiographic LA maximum volume in younger patients predict the success of RFCA.
Authors: Marijana Tadic; Cesare Cuspidi; Irena Ilic; Jelena Suzic-Lazić; Vladimir Zivanovic; Ljilja Jozika; Vera Celic Journal: Int J Cardiovasc Imaging Date: 2015-12-12 Impact factor: 2.357
Authors: Filip M Szymanski; Krzysztof J Filipiak; Anna E Platek; Anna Hrynkiewicz-Szymanska; Marcin Kotkowski; Edward Kozluk; Marek Kiliszek; Janusz Sierdzinski; Grzegorz Opolski Journal: Sleep Breath Date: 2015-01-08 Impact factor: 2.816
Authors: Jared W Magnani; Xiaoyan Yin; David D McManus; Michael L Chuang; Susan Cheng; Steven A Lubitz; Garima Arora; Warren J Manning; Patrick T Ellinor; Emelia J Benjamin Journal: J Am Heart Assoc Date: 2014-04-02 Impact factor: 5.501
Authors: Sebastian I Sarvari; Kristina H Haugaa; Thomas M Stokke; Hamza Z Ansari; Ida S Leren; Finn Hegbom; Otto A Smiseth; Thor Edvardsen Journal: Eur Heart J Cardiovasc Imaging Date: 2015-07-27 Impact factor: 6.875