| Literature DB >> 24167065 |
Shuntaro Takahashi1, Naoki Sugimoto.
Abstract
Under pressure: A DNA G-quadruplex was unfolded under high pressure, but crowding conditions repressed this effect owing to enthalpic contributions. Volumetric analysis showed that ethylene glycol or poly(ethylene glycol) decreased the volume change of the transition by more than fourfold owing to the alteration of the number and/or radii of hydrating water molecules.Entities:
Keywords: DNA structures; G-quadruplexes; gene expression; high pressure; thermodynamics
Mesh:
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Year: 2013 PMID: 24167065 DOI: 10.1002/anie.201307714
Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN: 1433-7851 Impact factor: 15.336