Literature DB >> 24166311

Inhibition of miRNA maturation by peptide nucleic acids.

Concetta Avitabile1, Enrica Fabbri, Nicoletta Bianchi, Roberto Gambari, Alessandra Romanelli.   

Abstract

Molecules able to interfere in miRNA genesis and function are potent tools to unravel maturation and processing pathways. Antisense oligonucleotides or analogs are actually employed for the inhibition of miRNA function. Here we illustrate how Peptide Nucleic Acids oligomers targeting pre-miRNA are exploited to inhibit miRNA maturation.

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Year:  2014        PMID: 24166311     DOI: 10.1007/978-1-62703-703-7_13

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  4 in total

Review 1.  Regulation of expression of O6-methylguanine-DNA methyltransferase and the treatment of glioblastoma (Review).

Authors:  Giulio Cabrini; Enrica Fabbri; Cristiana Lo Nigro; Maria Cristina Dechecchi; Roberto Gambari
Journal:  Int J Oncol       Date:  2015-05-29       Impact factor: 5.650

2.  Long non-coding RNA containing ultraconserved genomic region 8 promotes bladder cancer tumorigenesis.

Authors:  Michele Olivieri; Matteo Ferro; Sara Terreri; Montano Durso; Alessandra Romanelli; Concetta Avitabile; Ottavio De Cobelli; Anna Messere; Dario Bruzzese; Ivan Vannini; Luciana Marinelli; Ettore Novellino; Wei Zhang; Mariarosaria Incoronato; Gennaro Ilardi; Stefania Staibano; Laura Marra; Renato Franco; Sisto Perdonà; Daniela Terracciano; Bogdan Czerniak; Giovanna L Liguori; Vincenza Colonna; Muller Fabbri; Ferdinando Febbraio; George A Calin; Amelia Cimmino
Journal:  Oncotarget       Date:  2016-04-12

Review 3.  MicroRNAs in the prognosis and therapy of colorectal cancer: From bench to bedside.

Authors:  Kenneth Kw To; Christy Ws Tong; Mingxia Wu; William Cs Cho
Journal:  World J Gastroenterol       Date:  2018-07-21       Impact factor: 5.742

Review 4.  Noncoding RNA therapeutics - challenges and potential solutions.

Authors:  Melanie Winkle; Sherien M El-Daly; Muller Fabbri; George A Calin
Journal:  Nat Rev Drug Discov       Date:  2021-06-18       Impact factor: 84.694

  4 in total

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