| Literature DB >> 24166146 |
Kevin Rostasy1, Markus Reindl.
Abstract
The recent detection of aquaporin-4 (AQP4) and myelin oligodendrocyte glycoprotein (MOG) autoantibodies in acquired inflammatory demyelinating diseases, such as neuromyelitis optica, or acute disseminated encephalomyelitis, and multiple sclerosis, in children strongly indicates that B-cell-dependent mechanisms contribute to the pathogenesis. This review aims to give an overview of the role of autoantibodies in inflammatory demyelinating pediatric diseases, with a focus on antibodies to AQP4 and MOG. Georg Thieme Verlag KG Stuttgart · New York.Entities:
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Year: 2013 PMID: 24166146 DOI: 10.1055/s-0033-1358602
Source DB: PubMed Journal: Neuropediatrics ISSN: 0174-304X Impact factor: 1.947