Literature DB >> 24164687

Exacerbation phenotyping in chronic obstructive pulmonary disease.

Martin MacDonald1, Tony Korman, Paul King, Kais Hamza, Philip Bardin.   

Abstract

Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are crucial events but causes remain poorly defined. A method to clinically 'phenotype' AECOPD have been proposed, and 52 hospitalized chronic obstructive pulmonary disease exacerbations according to underlying aetiology have now been prospectively phenotyped. Multiple exacerbation phenotypes were identified. A subpopulation coinfected with virus and bacteria had a significantly longer length of hospital stay, and this pilot study indicates that exacerbation phenotyping may be advantageous.
© 2013 The Authors. Respirology © 2013 Asian Pacific Society of Respirology.

Entities:  

Keywords:  chronic obstructive pulmonary disease; clinical respiratory medicine; emphysema; infection and inflammation; viral infection

Mesh：

Year:  2013        PMID： 24164687     DOI： 10.1111/resp.12197

Source DB:  PubMed          Journal:  Respirology        ISSN： 1323-7799            Impact factor:   6.424


  11 in total

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8.  Exposure to common respiratory bacteria alters the airway epithelial response to subsequent viral infection.

Authors:  Carla Bellinghausen; Fahad Gulraiz; Alexandra C A Heinzmann; Mieke A Dentener; Paul H M Savelkoul; Emiel F Wouters; Gernot G Rohde; Frank R Stassen
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9.  A prospective, observational cohort study of the seasonal dynamics of airway pathogens in the aetiology of exacerbations in COPD.

Authors:  Tom M A Wilkinson; Emmanuel Aris; Simon Bourne; Stuart C Clarke; Mathieu Peeters; Thierry G Pascal; Sonia Schoonbroodt; Andrew C Tuck; Viktoriya Kim; Kristoffer Ostridge; Karl J Staples; Nicholas Williams; Anthony Williams; Stephen Wootton; Jeanne-Marie Devaster
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10.  MULTI-PHACET: multidimensional clinical phenotyping of hospitalised acute COPD exacerbations.

Authors:  Martin I MacDonald; Christian R Osadnik; Lauren Bulfin; Elizabeth Leahy; Paul Leong; Eskandarain Shafuddin; Kais Hamza; Paul T King; Philip G Bardin
Journal:  ERJ Open Res       Date:  2021-07-12
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