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Literature DB >> 24163745

Screening for lung cancer with low-dose computed tomography: a review of current status.

Henry M Marshall¹, Rayleen V Bowman, Ian A Yang, Kwun M Fong, Christine D Berg.

Abstract

Screening using low-dose computed tomography (CT) represents an exciting new development in the struggle to improve outcomes for people with lung cancer. Randomised controlled evidence demonstrating a 20% relative lung cancer mortality benefit has led to endorsement of screening by several expert bodies in the US and funding by healthcare providers. Despite this pivotal result, many questions remain regarding technical and logistical aspects of screening, cost-effectiveness and generalizability to other settings. This review discusses the rationale behind screening, the results of on-going trials, potential harms of screening and current knowledge gaps.

Entities: Disease Species

Keywords: Lung neoplasms/mortality; early detection of cancer/methods; helical computed; mass screening tomography

Year: 2013 PMID： 24163745 PMCID： PMC3804881 DOI： 10.3978/j.issn.2072-1439.2013.09.06

Source DB: PubMed Journal: J Thorac Dis ISSN： 2072-1439 Impact factor: 2.895

131 in total

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