Sir,We thank the correspondents for their interest and comments on our article.[12] We agree that the routine practice is to give antiemetics during surgery. However as discussed by us in the article, this would have confounded the effects of the antiemetic drugs on QTc interval. We do not have data on the incidence of nausea and vomiting as the aim of our study was to check the safety profile and not the efficacy. The antiemetics were given for prophylaxis and not treatment. We used 8mg of ondansetron and 1mg of granisetron as this was the standard of care in our institute that time and we wanted the study to reflect normal clinical practice.This study was conducted in 2006-2007 while the Food and Drugs Administration advisory was issued in 2011 as quoted by the correspondents. In 2006, this was the standard of care in our institute while granisetron was just launched that year in India.We hope this satisfies the queries raised and we once again thank them for their interest.