Literature DB >> 24163473

A case of triple vessel disease posted for buccal mucosal graft urethroplasty under low dose spinal anaesthesia with dexmedetomedine.

R Prabhavathi1, Narasimha P Reddy, Ts Chandra Sekhar, Vivek T Menacherry.   

Abstract

Entities:  

Year:  2013        PMID: 24163473      PMCID: PMC3800351          DOI: 10.4103/0019-5049.118526

Source DB:  PubMed          Journal:  Indian J Anaesth        ISSN: 0019-5049


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Sir, We report a case of stricture urethra in a 59 years male undergoing buccal mucosal graft (BMG) urethroplasty for partial segmental stricture at bulbourethral membrane, since buccal mucosa is the new gold standard for substitution urethroplasty.[1] On evaluation, patient gave a history of myocardial infarction 6 years back, with angiographic findings of 100% block in left anterior descending artery and 70% block in right coronary artery 60% block in left circumflex arteryalong with ostial lesions and diffuse atherosclerosis of all vessels, suggesting of triple vessel disease. As patient was not willing to accept the high risk associated with coronary artery bypass graft surgery as explained by the surgeons, he was not operated. Electrocardiography revealed signs of left ventricular hypertrophy. Patient was a known diabetic since 18 years and hypertensive since 8 years. His echo findings were left ventricular hypertrophy, mild aortic stenosis, moderate diastolic dysfunction with ejection fraction 36% and moderate mitral regurgitation, mild pulmonary hypertension and mild tricuspid regurgitation. Patient was instructed to discontinue antiplatelet medication 7 days prior and insulin on the day of surgery. Pre - operative vitals and haematological parameters were within normal limits. According to guidelines 2007 on perioperative cardiovascular evaluation and care for non - cardiac surgery, infrainguinal procedures can be performed under spinal or epidural anaesthesia with minimal hemodynamic changes if neuraxial blockade is limited to those dermatomes. Studies have shown that combined spinal-epidural anaesthesia, using low doses of local anaesthetics with additives, is effective and reduces the incidence of hypotension in caesarean section[234] and transurethral resection of prostrate.[5] 12 lead ECG and central venous pressure monitoring was done along with all other routine protocol. Epidural catheter was introduced at L1-L2 level and catheter was directed downward and tip was fixed at L3-L4 level. Then spinal anaesthesia was given in L4-L5 space. Patient received 2.5 mL of 0.25% bupivacaine (1.25 mL of 0.5% bupivacaine with 1.25 mL of 5% dextrose). In addition, 5 mic of dexmedetomedine was added. BMG was taken under local infiltration of 10 mL of 1% lignocaine and 100 mic of intravenous fentanyl without any hemodynamic alterations. Neither changes in blood pressure nor ECG changes were noticed. After 2 hours, 10 mL of 0.375% ropivacaine and 50 mic of fentanyl was given as epidural bolus. After 1 hour of bolus dose, a continuous epidural infusion was started with 0.2% ropivacaine 2 mic/mL of fentanyl at the rate of 7 mL/hour and continued up to 48 hours postoperatively. Low dose spinal and epidural anaesthesia in cardiac patient offer better response in-terms of maintaining hemodynamic stability, level of anaesthesia achieved would not be more than T10, which would be sufficient for BMG urethroplasty.
  5 in total

Review 1.  Buccal mucosal urethroplasty: is it the new gold standard?

Authors:  S Bhargava; C R Chapple
Journal:  BJU Int       Date:  2004-06       Impact factor: 5.588

Review 2.  Low-dose spinal anaesthesia for Caesarean section to prevent spinal-induced hypotension.

Authors:  Eva Roofthooft; Marc Van de Velde
Journal:  Curr Opin Anaesthesiol       Date:  2008-06       Impact factor: 2.706

3.  Comparison of intrathecal fentanyl and sufentanil in low-dose dilute bupivacaine spinal anaesthesia for transurethral prostatectomy.

Authors:  S Y Kim; J E Cho; J Y Hong; B N Koo; J M Kim; H K Kil
Journal:  Br J Anaesth       Date:  2009-09-28       Impact factor: 9.166

4.  Combined low-dose spinal-epidural anesthesia versus single-shot spinal anesthesia for elective cesarean delivery.

Authors:  D-H Choi; H-J Ahn; J-A Kim
Journal:  Int J Obstet Anesth       Date:  2005-10-26       Impact factor: 2.603

5.  Low-dose combined spinal-epidural anaesthesia vs. conventional epidural anaesthesia for Caesarean section in pre-eclampsia: a retrospective analysis.

Authors:  M Van de Velde; N Berends; B Spitz; A Teunkens; E Vandermeersch
Journal:  Eur J Anaesthesiol       Date:  2004-06       Impact factor: 4.330

  5 in total

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