Literature DB >> 24162760

Healing of human Achilles tendon ruptures: radiodensity reflects mechanical properties.

Thorsten Schepull1, Per Aspenberg.   

Abstract

PURPOSE: This study tests the idea of using radiodensity from computed tomography to quantitatively evaluate the healing of ruptured Achilles tendons.
METHODS: The radiodensity of the healing tendons in sixty-five patients who were treated for Achilles tendon rupture was measured. The hypothesis was that density would correlate with an estimate for e-modulus, derived from strain, measured by radiostereometry with different mechanical loadings.
RESULTS: Radiodensity 7 weeks after injury was decreased to 67 % (SD 11) of the contralateral, uninjured tendon. There was no improvement in radiodensity from 7 to 19 weeks, whereas at 1 year, it had increased to 106 % (SD 7). Only 2 of 52 measured values at 1 year were lower than the highest value at 19 weeks, i.e. there was minimal overlap. The variation in radiodensity could explain 80 % of the variation in e-modulus, but radiodensity correlated only weakly with e-modulus at each time point separately. At 1 year, both radiodensity and e-modulus correlated with functional results, although weakly.
CONCLUSIONS: From 19 weeks onwards, radiodensity appears to reflect mechanical properties of the tendon and might to some extent predict the final outcome. Radiodensity at 7 weeks is difficult to interpret, probably because it reflects both callus and damaged tissues.

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Year:  2013        PMID: 24162760     DOI: 10.1007/s00167-013-2720-8

Source DB:  PubMed          Journal:  Knee Surg Sports Traumatol Arthrosc        ISSN: 0942-2056            Impact factor:   4.342


  19 in total

1.  Current concepts in the rehabilitation of an acute rupture of the tendo Achillis.

Authors:  R S Kearney; M L Costa
Journal:  J Bone Joint Surg Br       Date:  2012-01

2.  Autologous platelets have no effect on the healing of human achilles tendon ruptures: a randomized single-blind study.

Authors:  Thorsten Schepull; Joanna Kvist; Hanna Norrman; Marie Trinks; Gösta Berlin; Per Aspenberg
Journal:  Am J Sports Med       Date:  2010-11-03       Impact factor: 6.202

3.  Outcome and prognostic factors of achilles rupture repair using a new scoring method.

Authors:  J Leppilahti; K Forsman; J Puranen; S Orava
Journal:  Clin Orthop Relat Res       Date:  1998-01       Impact factor: 4.176

4.  Early controlled tension improves the material properties of healing human achilles tendons after ruptures: a randomized trial.

Authors:  Thorsten Schepull; Per Aspenberg
Journal:  Am J Sports Med       Date:  2013-09-04       Impact factor: 6.202

5.  Marked pathological changes proximal and distal to the site of rupture in acute Achilles tendon ruptures.

Authors:  Nicola Maffulli; Umile Giuseppe Longo; Gayle D Maffulli; Carla Rabitti; Anil Khanna; Vincenzo Denaro
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2010-06-19       Impact factor: 4.342

6.  Are ultrasound and magnetic resonance imaging of value in assessment of Achilles tendon disorders? A two year prospective study.

Authors:  K M Khan; B B Forster; J Robinson; Y Cheong; L Louis; L Maclean; J E Taunton
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7.  The Achilles tendon Total Rupture Score (ATRS): development and validation.

Authors:  Katarina Nilsson-Helander; Roland Thomeé; Karin Grävare Silbernagel; Karin Grävare-Silbernagel; Pia Thomeé; Eva Faxén; Bengt I Eriksson; Jon Karlsson
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8.  [Functional treatment of acute rupture of the Achilles tendon. An experimental biomechanical study].

Authors:  H Thermann; O Frerichs; A Biewener; C Krettek; P Schandelmeier
Journal:  Unfallchirurg       Date:  1995-10       Impact factor: 1.000

9.  Long-term ultrasonographic features of the Achilles tendon after rupture.

Authors:  Robert R Bleakney; Cheryl Tallon; Jason K Wong; Kim Peng Lim; Nicola Maffulli
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10.  Mechanical properties during healing of Achilles tendon ruptures to predict final outcome: a pilot Roentgen stereophotogrammetric analysis in 10 patients.

Authors:  Thorsten Schepull; Joanna Kvist; Christer Andersson; Per Aspenberg
Journal:  BMC Musculoskelet Disord       Date:  2007-11-26       Impact factor: 2.362

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  10 in total

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Authors:  Mathias Wulf; Mihir Shanker; Michael Schuetz; Michael Lutz; Christian M Langton; Sue L Hooper; James E Smeathers; Torsten Brauner; Scott C Wearing
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2017-06-28       Impact factor: 4.342

2.  Validation of High-Resolution peripheral Quantitative Computed Tomography-Derived Achilles Tendon Properties Against Diagnostic Ultrasound.

Authors:  Hugo J W Fung; Angela M Cheung; Sunita Mathur; Eva Szabo; Andy K O Wong
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Authors:  Qi Zhang; Yehua Cai; Yinghui Hua; Jun Shi; Yuanyuan Wang; Yi Wang
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2016-06-24       Impact factor: 4.342

4.  Influence of a lower leg brace on traction force in healthy and ruptured Achilles tendons.

Authors:  Olof Helge Sandberg; Ida Dånmark; Pernilla Eliasson; Per Aspenberg
Journal:  Muscles Ligaments Tendons J       Date:  2015-07-03

5.  Substantial creep in healing human Achilles tendons. A pilot study.

Authors:  Per Aspenberg; Thorsten Schepull
Journal:  Muscles Ligaments Tendons J       Date:  2015-10-20

6.  Ruptured human Achilles tendon has elevated metabolic activity up to 1 year after repair.

Authors:  Pernilla Eliasson; Christian Couppé; Markus Lonsdale; René B Svensson; Christian Neergaard; Michael Kjær; Lars Friberg; S Peter Magnusson
Journal:  Eur J Nucl Med Mol Imaging       Date:  2016-04-13       Impact factor: 9.236

7.  A possible link between loading, inflammation and healing: Immune cell populations during tendon healing in the rat.

Authors:  Parmis Blomgran; Robert Blomgran; Jan Ernerudh; Per Aspenberg
Journal:  Sci Rep       Date:  2016-07-13       Impact factor: 4.379

8.  Transverse tendon stiffness is reduced in people with Achilles tendinopathy: A cross-sectional study.

Authors:  Evan Finnamore; Charlotte Waugh; Lyndal Solomons; Michael Ryan; Christopher West; Alexander Scott
Journal:  PLoS One       Date:  2019-02-20       Impact factor: 3.240

9.  Functional Outcomes of Achilles Tendon Minimally Invasive Repair Using 4- and 6-Strand Nonabsorbable Suture: A Cohort Comparison Study.

Authors:  Michael R Carmont; Jennifer A Zellers; Annelie Brorsson; Nicklas Olsson; Katarina Nilsson-Helander; Jon Karlsson; Karin Grävare Silbernagel
Journal:  Orthop J Sports Med       Date:  2017-08-23

10.  Assessment of the Effects of Si Addition to a New TiMoZrTa System.

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Journal:  Materials (Basel)       Date:  2021-12-10       Impact factor: 3.623

  10 in total

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