Literature DB >> 2416272

Activity of arildone with or without interferon against acute hemorrhagic conjunctivitis viruses in cell culture.

M P Langford, D J Carr, M Yin-Murphy.   

Abstract

Arildone (WIN 38020; 4-[6-(2-chloro-4-methoxyphenoxy)hexyl]-3,5-heptanedione) inhibited the infectivity of acute hemorrhagic conjunctivitis viruses in tissue culture. Arildone did not inhibit interferon (IFN) production or IFN activity. Treatment of cultures with combinations of arildone and IFN resulted in an additive inhibition of acute hemorrhagic conjunctivitis virus production.

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Year:  1985        PMID： 2416272      PMCID： PMC180309          DOI： 10.1128/AAC.28.4.578

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  10 in total

1.  Apollo 11 disease or acute hemorrhagic conjunctivitis: a pandemic of a new enterovirus infection of the eyes.

Authors:  R Kono
Journal:  Am J Epidemiol       Date:  1975-05       Impact factor: 4.897

2.  Inhibition of uncoating of poliovirus by arildone, a new antiviral drug.

Authors:  J J McSharry; L A Caliguiri; H J Eggers
Journal:  Virology       Date:  1979-09       Impact factor: 3.616

3.  Effect of interferon, elevated temperature, and cell type on replication of acute hemorrhagic conjunctivitis viruses.

Authors:  G J Stanton; M P Langford; S Baron
Journal:  Infect Immun       Date:  1977-11       Impact factor: 3.441

4.  Virus plaque-reduction assay for interferon: microplaque and regular macroplaque reduction assays.

Authors:  M P Langford; D A Weigent; G J Stanton; S Baron
Journal:  Methods Enzymol       Date:  1981       Impact factor: 1.600

5.  Antiviral activity of arildone on deoxyribonucleic acid and ribonucleic acid viruses.

Authors:  K S Kim; V J Sapienza; R I Carp
Journal:  Antimicrob Agents Chemother       Date:  1980-08       Impact factor: 5.191

6.  Prevention of human poliovirus-induced paralysis and death in mice by the novel antiviral agent arildone.

Authors:  M A McKinlay; J V Miralles; C J Brisson; F Pancic
Journal:  Antimicrob Agents Chemother       Date:  1982-12       Impact factor: 5.191

7.  Virus-specific, early appearing neutralizing activity and interferon in tears of patients with acute hemorrhagic conjunctivitis.

Authors:  M P Langford; J C Barber; V E Sklar; S W Clark; P A Patriarca; I M Onarato; M Yin-Murphy; G J Stanton
Journal:  Curr Eye Res       Date:  1985-03       Impact factor: 2.424

8.  Antibody and interferon act synergistically to inhibit enterovirus, adenovirus, and herpes simplex virus infection.

Authors:  M P Langford; A L Villarreal; G J Stanton
Journal:  Infect Immun       Date:  1983-07       Impact factor: 3.441

9.  Polio-like motor paralysis associated with acute hemorrhagic conjunctivitis in an outbreak in 1981 in Bombay, India: clinical and serologic studies.

Authors:  N H Wadia; S M Katrak; V P Misra; P N Wadia; K Miyamura; K Hashimoto; T Ogino; T Hikiji; R Kono
Journal:  J Infect Dis       Date:  1983-04       Impact factor: 5.226

10.  Human fibroblast interferon in tears of patients with picornavirus epidemic conjunctivitis.

Authors:  M P Langford; M Yin-Murphy; Y M Ho; J C Barber; S Baron; G J Stanton
Journal:  Infect Immun       Date:  1980-09       Impact factor: 3.441
  10 in total
  1 in total

Review 1.  Treatment of viral conjunctivitis with antiviral drugs.

Authors:  Chrysanthi L Skevaki; Ioanna E Galani; Michail V Pararas; Konstantina P Giannopoulou; Athanassios Tsakris
Journal:  Drugs       Date:  2011-02-12       Impact factor: 9.546
  1 in total

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