Literature DB >> 24162496

Joint mapping of quantitative trait loci using F2 populations.

W R Wu1, W M Li.   

Abstract

In this paper, the theory of joint mapping of quantitative trait loci is extended to F2 populations. Two independent regression equations, related to the additive and dominance effects respectively, are derived. Therefore, there are three alternative strategies for mapping QTLs, called additive-based mapping (ABM), dominance-based mapping (DBM) and additive-dominance-based mapping (ADBM). Simulation results have shown that ADBM is the most appropriate in most situations.

Year:  1996        PMID： 24162496     DOI： 10.1007/BF00230140

Source DB:  PubMed          Journal:  Theor Appl Genet        ISSN： 0040-5752            Impact factor:   5.699


  6 in total

1.  Inbreeding and Linkage.

Authors:  J B Haldane; C H Waddington
Journal:  Genetics       Date:  1931-07       Impact factor: 4.562

2.  Model fitting and model testing in the method of joint mapping of quantitative trait loci.

Authors:  W R Wu; W M Li
Journal:  Theor Appl Genet       Date:  1996-03       Impact factor: 5.699

3.  Estimating the locations and the sizes of the effects of quantitative trait loci using flanking markers.

Authors:  O Martínez; R N Curnow
Journal:  Theor Appl Genet       Date:  1992-12       Impact factor: 5.699

4.  A new approach for mapping quantitative trait loci using complete genetic marker linkage maps.

Authors:  W R Wu; W M Li
Journal:  Theor Appl Genet       Date:  1994-11       Impact factor: 5.699

5.  QTL analysis: a simple 'marker-regression' approach.

Authors:  M J Kearsey; V Hyne
Journal:  Theor Appl Genet       Date:  1994-11       Impact factor: 5.699

6.  Mapping mendelian factors underlying quantitative traits using RFLP linkage maps.

Authors:  E S Lander; D Botstein
Journal:  Genetics       Date:  1989-01       Impact factor: 4.562
  6 in total

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