Literature DB >> 24161316

New therapeutic targets for calcific aortic valve stenosis: the lipoprotein(a)-lipoprotein-associated phospholipase A2-oxidized phospholipid axis.

Ming-Yow Hung1, Joseph L Witztum2, Sotirios Tsimikas3.   

Abstract

Entities:  

Keywords:  Lp-PLA2; aortic stenosis; calcific aortic valve disease; lysophosphatidylcholine; valve interstitial cells

Mesh：

Substances：

Year:  2013        PMID： 24161316      PMCID： PMC5928500          DOI： 10.1016/j.jacc.2013.08.1639

Source DB:  PubMed          Journal:  J Am Coll Cardiol        ISSN： 0735-1097            Impact factor:   24.094


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  29 in total

Review 1.  Oxidized phospholipids on apoB-100-containing lipoproteins: a biomarker predicting cardiovascular disease and cardiovascular events.

Authors:  Adam Taleb; Joseph L Witztum; Sotirios Tsimikas
Journal:  Biomark Med       Date:  2011-10       Impact factor: 2.851

Review 2.  Lipoprotein(a): resurrected by genetics.

Authors:  F Kronenberg; G Utermann
Journal:  J Intern Med       Date:  2012-11-12       Impact factor: 8.989

3.  Lipoprotein(a) as a potential causal genetic risk factor of cardiovascular disease: a rationale for increased efforts to understand its pathophysiology and develop targeted therapies.

Authors:  Sotirios Tsimikas; Jennifer L Hall
Journal:  J Am Coll Cardiol       Date:  2012-08-21       Impact factor: 24.094

4.  Oxidative stress modulates osteoblastic differentiation of vascular and bone cells.

Authors:  N Mody; F Parhami; T A Sarafian; L L Demer
Journal:  Free Radic Biol Med       Date:  2001-08-15       Impact factor: 7.376

5.  Presence of oxidized low density lipoprotein in nonrheumatic stenotic aortic valves.

Authors:  M Olsson; J Thyberg; J Nilsson
Journal:  Arterioscler Thromb Vasc Biol       Date:  1999-05       Impact factor: 8.311

6.  Correlation between oxidized low density lipoproteins and von Willebrand factor in chronic renal failure.

Authors:  P Holvoet; J Donck; M Landeloos; E Brouwers; K Luijtens; J Arnout; E Lesaffre; Y Vanrenterghem; D Collen
Journal:  Thromb Haemost       Date:  1996-11       Impact factor: 5.249

7.  PAF-acetylhydrolase activity of Lp(a) before and during Cu(2+)-induced oxidative modification in vitro.

Authors:  S A Karabina; M C Elisaf; J Goudevenos; K C Siamopoulos; D Sideris; A D Tselepis
Journal:  Atherosclerosis       Date:  1996-08-23       Impact factor: 5.162

8.  Lowering plasma cholesterol levels halts progression of aortic valve disease in mice.

Authors:  Jordan D Miller; Robert M Weiss; Kristine M Serrano; Robert M Brooks; Christopher J Berry; Kathy Zimmerman; Stephen G Young; Donald D Heistad
Journal:  Circulation       Date:  2009-05-11       Impact factor: 29.690

9.  Association between plasma LDL particle size, valvular accumulation of oxidized LDL, and inflammation in patients with aortic stenosis.

Authors:  Dania Mohty; Philippe Pibarot; Jean-Pierre Després; Claude Côté; Benoit Arsenault; Amélie Cartier; Pierre Cosnay; Christian Couture; Patrick Mathieu
Journal:  Arterioscler Thromb Vasc Biol       Date:  2007-11-01       Impact factor: 8.311

10.  Oxidized phospholipids, lipoprotein(a), lipoprotein-associated phospholipase A2 activity, and 10-year cardiovascular outcomes: prospective results from the Bruneck study.

Authors:  Stefan Kiechl; Johann Willeit; Manuel Mayr; Brigitte Viehweider; Martin Oberhollenzer; Florian Kronenberg; Christian J Wiedermann; Sabine Oberthaler; Qingbo Xu; Joseph L Witztum; Sotirios Tsimikas
Journal:  Arterioscler Thromb Vasc Biol       Date:  2007-05-31       Impact factor: 8.311
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  15 in total

Review 1.  Lipoprotein-associated phospholipase A2: The story continues.

Authors:  Fubao Huang; Kai Wang; Jianhua Shen
Journal:  Med Res Rev       Date:  2019-05-29       Impact factor: 12.944

Review 2.  Imaging of oxidation-specific epitopes with targeted nanoparticles to detect high-risk atherosclerotic lesions: progress and future directions.

Authors:  Karen Briley-Saebo; Calvin Yeang; Joseph L Witztum; Sotirios Tsimikas
Journal:  J Cardiovasc Transl Res       Date:  2014-10-09       Impact factor: 4.132

3.  Lipoprotein-associated phospholipase A2 and aortic stenosis: biomarker or new target for an old foe?

Authors:  Donald Heistad; Hardik Doshi
Journal:  JACC Cardiovasc Imaging       Date:  2015-01

4.  Oxidized Phospholipids and Risk of Calcific Aortic Valve Disease: The Copenhagen General Population Study.

Authors:  Pia R Kamstrup; Ming-Yow Hung; Joseph L Witztum; Sotirios Tsimikas; Børge G Nordestgaard
Journal:  Arterioscler Thromb Vasc Biol       Date:  2017-06-01       Impact factor: 8.311

5.  Mipomersen, an antisense oligonucleotide to apolipoprotein B-100, reduces lipoprotein(a) in various populations with hypercholesterolemia: results of 4 phase III trials.

Authors:  Raul D Santos; Frederick J Raal; Alberico L Catapano; Joseph L Witztum; Elisabeth Steinhagen-Thiessen; Sotirios Tsimikas
Journal:  Arterioscler Thromb Vasc Biol       Date:  2015-01-22       Impact factor: 8.311

Review 6.  Calcific aortic stenosis.

Authors:  Brian R Lindman; Marie-Annick Clavel; Patrick Mathieu; Bernard Iung; Patrizio Lancellotti; Catherine M Otto; Philippe Pibarot
Journal:  Nat Rev Dis Primers       Date:  2016-03-03       Impact factor: 52.329

Review 7.  Role of oxidative stress in calcific aortic valve disease and its therapeutic implications.

Authors:  Harry Z E Greenberg; Guoan Zhao; Ajay M Shah; Min Zhang
Journal:  Cardiovasc Res       Date:  2022-05-06       Impact factor: 13.081

Review 8.  Innate and Adaptive Immunity in Calcific Aortic Valve Disease.

Authors:  Patrick Mathieu; Rihab Bouchareb; Marie-Chloé Boulanger
Journal:  J Immunol Res       Date:  2015-05-03       Impact factor: 4.818

9.  Incidence of elevated lipoprotein (a) levels in a large cohort of patients with cardiovascular disease.

Authors:  Frank van Buuren; Dieter Horstkotte; Cornelius Knabbe; Dennis Hinse; Klaus Peter Mellwig
Journal:  Clin Res Cardiol Suppl       Date:  2017-03

10.  ApoB/ApoA-I Ratio is Associated With Faster Hemodynamic Progression of Aortic Stenosis: Results From the PROGRESSA (Metabolic Determinants of the Progression of Aortic Stenosis) Study.

Authors:  Lionel Tastet; Romain Capoulade; Mylène Shen; Marie-Annick Clavel; Nancy Côté; Patrick Mathieu; Marie Arsenault; Élisabeth Bédard; Alexe Tremblay; Marilie Samson; Yohan Bossé; Jean G Dumesnil; Benoit J Arsenault; Jonathan Beaudoin; Mathieu Bernier; Jean-Pierre Després; Philippe Pibarot
Journal:  J Am Heart Assoc       Date:  2018-02-10       Impact factor: 5.501
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